E2F1 (NM_005225) Human 3' UTR Clone

Specifications

Product Data
Product Name	E2F1 (NM_005225) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	E2F-1; RBAP1; RBBP3; RBP3
ACCN	NM_005225
Insert Size	1269 bp
Sequence Data	Insert Sequence (showhide) >SC213584 3' UTR clone of NM_005225 The sequence shown below is from the reference sequence of NM_005225. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CTCTTCGACTGTGACTTTGGGGACCTCACCCCCCTGGATTTCTGACAGGGCTTGGAGGGACCAGGGTTTC CAGAGATGCTCACCTTGTCTCTGCAGCCCTGGAGCCCCCTGTCCCTGGCCGTCCTCCCAGCCTGTTTGGA AACATTTAATTTATACCCCTCTCCTCTGTCTCCAGAAGCTTCTAGCTCTGGGGTCTGGCTACCGCTAGGA GGCTGAGCAAGCCAGGAAGGGAAGGAGTCTGTGTGGTGTGTATGTGCATGCAGCCTACACCCACACGTGT GTACCGGGGGTGAATGTGTGTGAGCATGTGTGTGTGCATGTACCGGGGAATGAAGGTGAACATACACCTC TGTGTGTGCACTGCAGACACGCCCCAGTGTGTCCACATGTGTGTGCATGAGTCCATGTGTGCGCGTGGGG GGGCTCTAACTGCACTTTCGGCCCTTTTGCTCTGGGGGTCCCACAAGGCCCAGGGCAGTGCCTGCTCCCA GAATCTGGTGCTCTGACCAGGCCAGGTGGGGAGGCTTTGGCTGGCTGGGCGTGTAGGACGGTGAGAGCAC TTCTGTCTTAAAGGTTTTTTCTGATTGAAGCTTTAATGGAGCGTTATTTATTTATCGAGGCCTCTTTGGT GAGCCTGGGGAATCAGCAAAGGGGAGGAGGGGTGTGGGGTTGATACCCCAACTCCCTCTACCCTTGAGCA AGGGCAGGGGTCCCTGAGCTGTTCTTCTGCCCCATACTGAAGGAACTGAGGCCTGGGTGATTTATTTATT GGGAAAGTGAGGGAGGGAGACAGACTGACTGACAGCCATGGGTGGTCAGATGGTGGGGTGGGCCCTCTCC AGGGGGCCAGTTCAGGGCCCCAGCTGCCCCCCAGGATGGATATGAGATGGGAGAGGTGAGTGGGGGACCT TCACTGATGTGGGCAGGAGGGGTGGTGAAGGCCTCCCCCAGCCCAGACCCTGTGGTCCCTCCTGCAGTGT CTGAAGCGCCTGCCTCCCCACTGCTCTGCCCCACCCTCCAATCTGCACTTTGATTTGCTTCCTAACAGCT CTGTTCCCTCCTGCTTTGGTTTTAATAAATATTTTGATGACGTTTGGGCCGGGTTTTGGGACTCTGTTGG GAACATTTCGGGGCGGGAGAGGCCAAGGTTGCTGGGGAAATGCCCATTCTCCACTTCCCTTCTCCCTGTC CGTGCCCGATTTGATTTGAGCCTCATAACTCGAAGAAAGGTCAGCTTCCTCGCTGTTTTGGTCCTAACTC AAAAGCAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005225.2
Synonyms	E2F-1; RBAP1; RBBP3; RBP3
Summary	The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]
Locus ID	1869

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