UPF2 (NM_015542) Human 3' UTR Clone

Specifications

Product Data
Product Name	UPF2 (NM_015542) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HUPF2; RENT2; smg-3
ACCN	NM_015542
Insert Size	1306 bp
Sequence Data	Insert Sequence (showhide) >SC213747 3’UTR clone of NM_015542 The sequence shown below is from the reference sequence of NM_015542. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATCTTTAAGACTGGTGGGAGGAGACGTTGATCCAGCAGCACGTGTCATTTCATTAGGTCCTGTATCTGA TGTTGTGGTTAGTGGAGTCCTCCAGCAATTGAATGAGAGCAGTGGACACATCTCAGCAGGTCGGTCTAG AGAGTTGCGAATCTAAACCTGGGACAGGCTGGGGCCAGGAGGCAGAAACACCAGCCTCTGCCAACACCG GAACAAGCCGACGCTTCCAGACAAGGCGGAAAAGGCCTTTTGTAATGGAAATCTCGCGAGGGTTAATCT TCTCTTGAGAATGGCAGTCAAGAAATGAGATGGTTCACTTGACTACTGAGCAGTTACACCAAGGAGAGC GTGAAGGAGATGATTGAGCCAGAGAAGAAACGGGTTGTGATGGTAATGGTGTGGGGGAAATGAACTTGA GCTTTAAACTTGATTTGAGTTTCAGTGTCTCTGAATTGAACATCCCACGTTGGAAGAAGATACATTTGG GGGCTCCAGGACTACAGTAGAAAAGTATAGAGCAAGCAGGAAAATCTTCTAGTAAAACTTACATGCAGG ACAACAAAATGATGAAAGATATCCAAATACCAGATAATCCACCAGGAAGGCTTTTGTTTAGGAATTTGT TTCAAGAGGAACAAGGGATGAGGGAGAAAAATCCGTTTTATCCATCAGAGTCAGTGCTATAAAATTGCC TATTAAGGTAAAAGAAAAATGTGGAGACTATTTTACTATACAGAGAGCATTAATTCAGATGGCTTAGAA AAGTGATACCAGCCCAAGAACAGGGATCTAGGTGAGCCCATTGTAAGTATCATTGAAAACAAAACATGC CCGTCAACATGTCACAGAAAACGAACGAAGGACAACAAGAAGTGGATGAGAATATTTTGTTGACCTTCA TGGGTTTACAGCCTCTGTCTCTAAACAAAGTATGGAAACAAGTAGAGCTTTTATTTTGCTTTTGTTTTT GTTTTGTTTTTTTTTTTGTTTTCCCCCACTAAATAGAAATGAGGGTCCTTAGTCTGTTTCTGACAATCT GTTAATTTCTTAGGACAGCTGTCTTTGGTTTGCTTTCCAGCAGGCGTAGTATATTTAGTCGGAGAGCAC ATCTGTATGCGACAACTTGATTACATCTTTTTTTCTAGCTATTTTGCATTTTTTCTTTTACCATGTTTC AGTTTCTGCATGTAGATTTAAATAAAAAACAAAACTTGTAAAGTTGTAACATTTCACATGGAAATGCTG CCCAATCTTCACCAGCTTCAGAAATCTGACCTTTGCCGATGCTGCAATAAAGTGTTGTAATTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_015542.4
Synonyms	HUPF2; RENT2; smg-3
Summary	This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq, Jul 2008]
Locus ID	26019
MW	50.6

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