CYP7A1 (NM_000780) Human 3' UTR Clone

Specifications

Product Data
Product Name	CYP7A1 (NM_000780) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CP7A; CYP7; CYPVII
ACCN	NM_000780
Insert Size	1334 bp
Sequence Data	Insert Sequence (showhide) >SC213775 3' UTR clone of NM_000780 The sequence shown below is from the reference sequence of NM_000780. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CGCCATTGAATGATATTGAATTTAAATATAAATTCAAGCATTTGTGAATACATGGCTGGAATAAGAGGAC ACTAGATGATATTACAGGACTGCAGAACACCCTCACCACACAGTCCCTTTGGACAAATGCATTTAGTGGT GGTAGAAATGATTCACCAGGTCCAATGTTGTTCACCAGTGCTTGCTTGTGAATCTTAACATTTTGGTGAC AGTTTCCAGATGCTATCACAGACTCTGCTAGTGAAAAGAACTAGTTTCTAGGAGCACAATAATTTGTTTT CATTTGTATAAGTCCATGAATGTTCATATAGCCAGGGATTGAAGTTTATTATTTTCAAAGGAAAACACCT TTATTTTATTTTTTTTCAAAATGAAGATACACATTACAGCCAGGTGTGGTAGCAGGCACCTGTAGTCTTA GCTACTCGAGAGGCCAAAGAAGGAGGATGGCTTGAGCCCAGGAGTTCAAGACCAGCCTGGACAGCTTAGT GAGATCCCGTCTCCGAAGAAAAGATATGTATTCTAATTGGCAGATTGTTTTTTCCTAAGGAAACTGCTTT ATTTTTATAAAACTGCCTGACAATTATGAAAAAATGTTCAAATTCACGTTCTAGTGAAACTGCATTATTT GTTGACTAGATGGTGGGGTTCTTCGGGTGTGATCATATATCATAAAGGATATTTCAAATGATTATGATTA GTTATGTCTTTTAATAAAAAGGAAATATTTTTCAACTTCTTCTATATCCAAAATTCAGGGCTTTAAACAT GATTATCTTGATTTCCCAAAAACACTAAAGGTGGTTTTATTTTCCCTTCATGTTTTAACTTATTGTTGCT GAAAACTCTATGTCCGGCTTTAACTATCTTCTCTATATTTTTATTTCATTCACATTAATGAGAAGAGTTT TCTCAGAGATTAAAAAAGGTAGTTTTTCTGTCATTGTTAAATACACATTATCACTGAAAAAATGTAGCTT TTATGTGATATGTTTTAAAGTTAAAACTGGATGGAAATAGCCATTTGGAAGCTTTGGTTATGAAACATGT GGAGTGTATTAAGTGCAGCTTGACATTATGTTTTATTTAAATGCTTTTTATCGCTAAATGACTTGCAGAT GAAAAAAACTAAGGTGACTCGAGTGTTTAAATGCTGTGTACAACAATGCTTTGATAAAATATTTTAAGTA TGAGTTATCAGCTCTATGTCAATTGATATTTCTGTGTAGTATTTATATTTAAATTATATTTACCTTTTTG CTTATTTTACAAATATTAAGAAAATATTCTAACATTTGATAATTTTGAAATGATTCATCTTTCAGAAATA AAAG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000780.3
Synonyms	CP7A; CYP7; CYPVII
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010]
Locus ID	1581

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