Sorbitol Dehydrogenase (SORD) (NM_003104) Human 3' UTR Clone

Specifications

Product Data
Product Name	Sorbitol Dehydrogenase (SORD) (NM_003104) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HEL-S-95n; RDH; SDH; SORD1; SORDD; XDH
ACCN	NM_003104
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC213863 3’UTR clone of NM_003104 The sequence shown below is from the reference sequence of NM_003104. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGTGTGACCCCAGTGACCAGAATCCCTGATGTTAATGGGCTCTGCCCTCATCCCCACAGTCTTGGGAT CTCAGGGCACAATGGCTGGACATGGGTGGGCTCTGATGCAGAACTTTCTCTTTTGAATGTTAAGAATAA CTAATACAATTCATTGTGAACAGAAGTCCTTAAGCAGAGGAATTGGTGTGCCTTAAAGATACAATCTGG GATAGTTTGGGGGAACTTGTAGCCAGAATGCCCTGTTCATGCTGAGCAAAGTTCAGCAAGTAGAGCAGA GTTTGGCAGGCAGGTGCCAGGAACTCCCCTTCTTCCTGGAGTGCCTTCATTGAGGAAGGAAATCTGGCC CTTGGGTTTCCTGGTTCCACTGCTACTGACCCAGAGGGGAATGAGGGCTGAGTTATGAAAAGATAACTT CATGAAGACTTAACTGGCCCAGAAGCTGATTTTCATGAAAATCTGCCACTCAGGGTCTGGGATGAAGGC TTGTCAGCACTTCCAGTTTAGAACGCAATGTTTCTAGAGACATATTGGCTGTTTGTTTTGATGATAAAA GGAGAATAAGAAAAGGCATCACTTTCCTGGATCCAGGATAATTTTTAAACCAATCAAATGAAAAAAACA AACAAACAAAAAAGGAAATGTCATGTGAGGTTAAACCAGTTTGCATTCCCCTAATGTGGAAAAAGTAAG AGGACTACTCAGCACTGTTTGAAGATTGCCTCTTCTACAGCTTCTGAGAATTGTGTTATTTCACTTGCC AAGTGAAGGACCCCCTCCCCAACATGCCCCAGCCCACCCCTAAGCATGGTCCCTTGTCACCAGGCAACC AGGAAACTGCTACTTGTGGACCTCACCAGAGACCAGGAGGGTTTGGTTAGCTCACAGGACTTCCCCCAC CCCAGAAGATTAGCATCCCATACTAGACTCATACTCAACTCAACTAGGCTCATACTCAATTGATGGTTA TTAGACAATTCCATTTCTTTCTGGTTATTATAAACAGAAAATCTTTCCTCTTCTCATTACCAGTAAAGG CTCTTGGTATCTTTCTGTTGGAATGATTTCTATGAACTTGTCTTATTTTAATGGTGGGTTTTTTTTCTG GTAAGATTTAGACCTAAATCGCATCATGCCAACTTGTGACTTTGAGACTATTCATCAAGAATGAGGATA TAGTAGCCATGACATAGCTTGAGCTATAGCCTTTAATTCCTTACTTTGGCTATGGGTGGAGGGTGAGTT TGAAGAGGTTCTGATTTTCTTGTAACCTGGGAAAGCCATGACCTTGTGCCCGATTCTTTCAGATTGCTT TGGGTAATAAATATTGGTGGTGGTATCTGACTCATGCTGCTGTTTATGGTCCTGTTTAGTGGGGAATGG ACTCAGGTTACCCATTTCCCAGAGGGAAGGATCCCAGGATTTTTGAAGGTTACATATTTTCTGTACCAA ATATAATTTCATTGACATGAATTATCTCTAATCCTCATGACAAGCCACATACACAATCATTTTGTAGAT AAAGAAGATATAAATGCCAGAGGAGACCTTAAGATTGTCTTACAACACAACCCTTCAGTTAACGAGAGA GGAAATTGAGGCTCAGATTGGGGAAGTGACTTGGCAAATCACACAGTGGGTTAGTCAATGGCCCAGGAT TAGACAGAACCCAGGAATCCTGACATCAAATCCTTTACAACATGCTGCCTCTCATAGGCCTGAGGTGTC CAGTCCTAGAGGACAAATGATGCTCCCCATGCCACCACCCCCACCAAGCAGCTCCTACTGATGAGAAGA TGCACTAAGCAGTCTTGGTGGAAACATCTTCCTCACGCCCTGTGCCCCCTTTCAGGTGCCCAGAGAAGG AGCTCCAGTGTCTGCTTCAGCCAGGGCTTTAAGAGAGAAGGAAGCTGGGAGTGAGGGGCAGAGGCTCTA CCAGAGAATGTCTGCTGGTGTCTTGGAGGCACTTCCTGCAGCCTATGCATGCCTCGTGAAGCCATTTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003104.6
Synonyms	HEL-S-95n; RDH; SDH; SORD1; SORDD; XDH
Summary	Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
Locus ID	6652
MW	75.7

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