CCR1 (NM_001295) Human 3' UTR Clone

Specifications

Product Data
Product Name	CCR1 (NM_001295) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD191; CKR-1; CKR1; CMKBR1; HM145; MIP1aR; SCYAR1
ACCN	NM_001295
Insert Size	1565 bp
Sequence Data	Insert Sequence (showhide) >SC215242 3’UTR clone of NM_001295 The sequence shown below is from the reference sequence of NM_001295. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGGGAGCATGAACTCTCTGCTGGGTTCTGACTCAGACCATAGGAGGCCAACCCAAAATAAGCAGGCGTG ACCTGCCAGGCACACTGAGCCAGCAGCCTGGCTCTCCCAGCCAGGTTCTGACTCTTGGCACAGCATGGA GTCACAGCCACTTGGGATAGAGAGGGAATGTAATGGTGGCCTGGGGCTTCTGAGGCTTCTGGGGCTTCA GTCTTTTCCATGAACTTCTCCCCTGGTAGAAAGAAGATGAATGAGCAAAACCAAATATTCCAGAGACTG GGACTAAGTGTACCAGAGAAGGGCTTGGACTCAAGCAAGATTTCAGATTTGTGACCATTAGCATTTGTC AACAAAGTCACCCACTTCCCACTATTGCTTGCACAAACCAATTAAACCCAGTAGTGGTGACTGTGGGCT CCATTCAAAGTGAGCTCCTAAGCCATGGGAGACACTGATGTATGAGGAATTTCTGTTCTTCCATCACCT CCCCCCCCCCGCCACCCTCCCACTGCCAAAGAACTTGGAAATAGTGATTTCCACAGTGACTCCACTCTG AGTCCCAGAGCCAATCAGTAGCCAGCATCTGCCTCCCCTTCACTCCCACCGCAGGATTTGGGCTCTTGG AATCCTGGGGAACATAGAACTCATGACGGAAGAGTTGAGACCTAACGAGAAATAGAAATGGGGAACTAC TGCTGGCAGTGGAACTAAGAAAGCCCTTAGGAAGAATTTTTATATCCACTAAAATCAAACAATTCAGGG AGTGGGCTAAGCACGGGCCATATGAATAACATGGTGTGCTTCTTAAAATAGCCATAAAGGGGAGGGACT CATCATTTCCATTTACCCTTCTTTTCTGACTATTTTTCAGAATCTCTCTTCTTTTCAAGTTGGGTGATA TGTTGGTAGATTCTAATGGCTTTATTGCAGCGATTAATAACAGGCAAAAGGAAGCAGGGTTGGTTTCCC TTCTTTTTGTTCTTCATCTAAGCCTTCTGGTTTTATGGGTCAGAGTTCCGACTGCCATCTTGGACTTGT CAGCAAAAAAAAAAAATAATAATAATAATAAGGCCTGCTGTGTAAGCTGACAGTATTTGTAGCTGATAG GGGGTTGGGAGGAAAGTGTCTACTAGGAGGGTGGGGTGAGATTCTGTGTTGATGTAGGAGGCCGAGAAG GCCCTTAACTCAAAGTAGCTTATTTATCCAAAATGTTCTGGATGCATCATCTCCAACCAAGGACCCCTT ATTTATCATGCCTTTGTTCTCTTTTCCCTCAGATGTATATTTCTTTAAAAATAATTTTCCTAATAACAA AACTTATTTCTAAAACAGCTTAAAAATTCAAAGAAAAACCCCAAACACTGACATTACCTACACTTCCAC TACCCAAAGACAAAATGTGCCCACTGTGTGCTTTTGAGTGTATTTTCTTTTAGTTTGTTTTTTGTTGGG TGCATATTTATGATAATAACAATGATGGACTTCAATTGTACTCACTGTTCTATTGTTGGTTTTAATTAG CAGCAAGTTGTGATCACTTTCCCAGGTGAATAAATCATTTCAAAGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001295.3
Synonyms	CD191; CKR-1; CKR1; CMKBR1; HM145; MIP1aR; SCYAR1
Summary	This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
Locus ID	1230
MW	58.8

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