ZNF451 (NM_015555) Human 3' UTR Clone

Specifications

Product Data
Product Name	ZNF451 (NM_015555) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	COASTER; dJ417I1.1
ACCN	NM_015555
Insert Size	1866 bp
Sequence Data	Insert Sequence (showhide) >SC216674 3’UTR clone of NM_015555 The sequence shown below is from the reference sequence of NM_015555. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCTATTAGAAGAAGTCTTGAGGAAATGTAATTAAAGATATTACCACACAACATCAAGTGGCCTTGAAGA GACTGAGATAACGAATTCTTGAGTTTGTTTTCTAAAGGAGACCAGAAATCCACTATTACAAATGTATTT GAAAACATGTTTTTGCTTTCATATGTTCAAAATCTGATCTTTGTTTTGTATTTTTGTGCTAATGTGCAA ACATGTACAGAAGAAATAGAATACATGTTCATGCAAATATAAATTATGTATTCTAATATAGGTGTAACA GTTTCCCAGTTAACTTTGAATTTATATATTTAGATTTAAAGGATTAAAAAAAAGGAAAGCTCTTGACAG TTGTTTCCCAAATAGCATTAGTTCTTTAATTTTATTTGTACTGTACAAATGATGCTAGTTTATTTTTTT AGCAGTGAAAATGAATATAAAAAAGGTGACATAGGTCAAGTTTTCCATAAATTCTACTTCTCATGTGGC ACTATTATATAATACCTTTGAGATCTTTGTTTATGTTTATTAGAAGAGGGTAATGGAAACTGATCATGG AAACATTTAAAATTTTATCAGCAATGTTCTTTGTGGGTGCCATGCATATGTAAATTATTGCTTTAATTA GAGCAGCACATTGCTAAAATAAAAAATACACCTTAATTTTTAAGAAATAATTTAAATGAAACAATTTCC ATTCCTTTTACCTGCTTAGACTTTTATGTGACTTGTATGGTCTCCTGGTTAAAGGGAATGGTGTCAGAA TATTTGCATAAAATTATTTTTCATAACAGTCCTTTTTTATATATTGGTGTAAACATAATATTCTTCAAG AAATAATGTTGAAAGCCTACTCAGGAATAATCTTCCTTAACTCTTTAAATTTTTATTTCATGTGAAGTG TTTTCAGTTTAGTTATTCACTGAATTGTCAGTTTCCTTCATTTGGTATTACATATTTAATTCTTAAATA TTGAGGCCCCATTGTGAGTAATAAAAAATACGACATAAGTAGAAGACTAAGAAGGGCTTGTCATATTAT CTTTGTGTATATGCTTCATGTTATTTAACCAGAAATGTCTTATCTCTAAAAATTTTTAGTAGTAATTAT TTACCAAACTTAAAAACATTTCTATAAATATAAAGCTTTTCTTTATATTTAAGACAAAATATAAAGGCT AGAATTTGGTTCCTTCTCTGTAACACTAAATATTTTAGTGTGAAATTGAATTTTTTTATTACTATAGTC TTTTCAATCTATAATTTGTGTTTTTAATTTCTTGATATGTCACTTCTGTTCCTCCCTGCTTGCATTTTT TAAAAACTAGACATTGTGGCTTGAGAATTTATCAATCATCTTTCCGAAATGACCACATTGTGCTTTTAG TTTGTATGTTTAAGTGGTCAAGCAAGGCTCTAGGAGGTAGTCACTGAGCTGGACCTTAAACACATCTGC AGGAGCTCACAAAATGGGAGCAAAAGAGGCATTCCAGAAAGAAGAGTAGTTAAGCAGATGTGGGGGCAG GGCAAGAGGAGACAGCACCTTGTTGCCAGAGATTCTACACAAAGGTGTGATGGACACTGATGCTCTATT AAGAAGCTTTTGTGGTGTGTGTGGTAGAGAATAATTAAGGCTTCTGATAAGACAGGAAAGGGATATTTC ATCATGACTGTTAAGAAAAGGTAACTGGGTTGTTTAATGTTTTAATTGATAATTGTCACTGATCGTATT TCTACTTGTTAAATAATTAAAAATCATCTTAAAATTCATACTTTGACTTTAATTTAGACACAAGGAGAT GTAATCGCTGTGTAACATCAGAGAAAGCTATATGGATTATCGTCAGAAGTAAATGTTTCTAACATTGAC AAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_015555.3
Synonyms	COASTER; dJ417I1.1
Summary	E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation (By similarity). Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9' (PubMed:24324267). Plays a role in regulating the transcription of AR targets (PubMed:18656483).[UniProtKB/Swiss-Prot Function]
Locus ID	26036
MW	73

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