Mtm1 (NM_001164193) Mouse Untagged Clone
CAT#: MC208991
Mtm1 (untagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1), transcript variant 5, (10ug)
CNY 1,320.00
CNY 3,990.00
Product images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | AF073996; mKIAA4176; Mtm |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites | SgfI-MluI |
ACCN | NM_001164193 |
Insert Size | 489 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001164193.1, NP_001157665.1 |
RefSeq Size | 770 bp |
RefSeq ORF | 489 bp |
Locus ID | 17772 |
Gene Summary | Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology (By similarity). Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning (PubMed:21135508). Required for skeletal muscle maintenance but not for myogenesis (PubMed:12391329). In skeletal muscles, stabilizes MTMR12 protein levels (PubMed:23818870).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (5) differs in the 5' UTR and contains an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 3, which has a shorter and distinct C-terminus, compared to isoform 1. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG224660 | Mtm1 (tGFP-tagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1) transcript variant 5, (10ug) |
CNY 2,090.00 |
|
MR224660 | Mtm1 (Myc-DDK-tagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1), transcript variant 5 |
CNY 1,900.00 |
|
MR224660L3 | Lenti ORF clone of Mtm1 (Myc-DDK-tagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1), transcript variant 5 |
CNY 3,800.00 |
|
MR224660L4 | Lenti ORF clone of Mtm1 (mGFP-tagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1), transcript variant 5 |
CNY 3,800.00 |