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Tollip (NM_023764) Mouse Untagged Clone
CAT＃: MC209983
Tollip (untagged) - Mouse toll interacting protein (Tollip), (10ug)
CNY 2,640.00
CNY 5,130.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 4930403G24Rik; 4931428G15Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_023764 |
| Insert Size | 825 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_023764.3, NP_076253.1 |
| RefSeq Size | 3705 bp |
| RefSeq ORF | 825 bp |
| Locus ID | 54473 |
| UniProt ID | Q9QZ06 |
| Gene Summary | Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Green Tea Polyphenol EGCG Upregulates Tollip Expression by Suppressing Elf-1 Expression
,Kumazoe, M;Yamashita, M;Nakamura, Y;Takamatsu, K;Bae, J;Yamashita, S;Yamada, S;Onda, H;Nojiri, T;Kangawa, K;Tachibana, H;,
J. Immunol.
,PubMed ID 28954885
[TOLLIP]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG203682 | Tollip (tGFP-tagged) - Mouse toll interacting protein (Tollip) |
CNY 4,370.00 |
|
| MR203682 | Tollip (Myc-DDK-tagged) - Mouse toll interacting protein (Tollip) |
CNY 3,600.00 |
|
| MR203682L3 | Lenti ORF clone of Tollip (Myc-DDK-tagged) - Mouse toll interacting protein (Tollip) |
CNY 5,890.00 |
|
| MR203682L4 | Lenti ORF clone of Tollip (mGFP-tagged) - Mouse toll interacting protein (Tollip) |
CNY 5,890.00 |
