Ptprs (NM_011218) Mouse Tagged ORF Clone
CAT#: MG222172
- TrueORF®
Ptprs (tGFP-tagged) - Mouse protein tyrosine phosphatase receptor type S (Ptprs), (10ug)
ORF Plasmid: DDK
"NM_011218" in other vectors (2)
Need custom modification / cloning service?
Get a free quote
CNY 15,580.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | AL022616; PTP; PTP-NU3; PTPNU-3; PTPsigma; Ptpt9; R-PTP-S; RPTPsigma |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MG222172 representing NM_011218
Red=Cloning site Blue=ORF Green=Tags(s) ATGGCGCCCACCTGGAGTCCCAGCGTGGTGTCTGTGGTGGGTCCTGTGGGGCTCTTCCTCGTACTGCTGG CCAGAGGATGCTTGGCTGAAGAACCACCCAGGTTTATCAGAGAGCCCAAGGATCAGATTGGAGTGTCGGG AGGCGTGGCCTCCTTCGTGTGCCAGGCCACGGGTGATCCTAAGCCACGGGTGACCTGGAACAAGAAGGGC AAGAAAGTGAACTCACAGCGCTTCGAGACCATTGACTTTGACGAGAGCTCTGGGGCGGTCCTGAGGATCC AGCCACTTCGGACGCCTCGGGATGAGAACGTGTACGAGTGTGTGGCCCAGAACTCGGTGGGCGAAATCAC AATTCATGCAAAGCTCACCGTCCTTCGAGAGGACCAGCTGCCTCCTGGCTTCCCCAACATTGACATGGGC CCCCAGTTGAAGGTTGTAGAGCGCACACGCACAGCCACCATGCTCTGTGCTGCCAGCGGGAACCCGGACC CTGAGATCACCTGGTTTAAGGACTTCCTGCCTGTGGACCCCAGTGCCAGCAACGGGCGGATCAAGCAGCT TCGATCAGGTGCCCTGCAGATTGAGAGCAGCGAGGAGACAGACCAGGGCAAGTACGAGTGTGTGGCCACC AACAGCGCTGGGGTGCGCTACTCATCACCTGCCAACCTCTACGTGCGAGTCCGCCGTGTGGCCCCACGCT TCTCCATCCTGCCCATGAGCCACGAGATCATGCCCGGTGGGAATGTGAATATCACTTGTGTGGCCGTGGG CTCACCCATGCCCTACGTGAAATGGATGCAGGGGGCCGAGGACCTGACGCCTGAGGATGACATGCCCGTG GGTCGGAATGTTCTAGAACTCACGGATGTCAAGGACTCAGCTAACTACACTTGTGTGGCCATGTCCAGCC TGGGTGTGATCGAGGCCGTGGCCCAGATCACTGTAAAATCTCTCCCCAAAGCCCCTGGGACTCCTGTGGT GACGGAGAACACTGCCACCAGTATCACTGTCACATGGGACTCGGGCAACCCTGACCCCGTGTCCTACTAC GTAATTGAGTATAAGTCCAAAAGCCAGGATGGGCCGTATCAGATCAAAGAAGACATCACCACCACGCGCT ACAGCATCGGAGGCCTGAGCCCCAATTCTGAGTATGAGATCTGGGTGTCAGCTGTCAACTCCATTGGCCA GGGCCCTCCCAGTGAATCGGTGGTGACCCGCACAGGTGAGCAGGCACCAGCCAGCGCTCCCAGGAATGTT CAGGCCCGCATGCTCAGCGCCACCACCATGATCGTGCAGTGGGAGGAGCCTGTGGAGCCCAATGGCCTGA TCCGTGGCTACCGTGTCTACTATACCATGGAGCCGGAACACCCAGTGGGCAACTGGCAGAAACACAATGT GGACGACAGTCTCCTGACCACTGTGGGCAGCCTGCTGGAAGACGAGACCTACACCGTGCGCGTGCTCGCC TTCACGTCGGTGGGCGACGGACCACTGTCAGACCCCATCCAGGTCAAGACCCAGCAGGGAGTTCCTGGCC AGCCCATGAACTTGCGGGCTGAGGCCAAGTCAGAGACCAGCATTGGGCTCTCGTGGAGTGCACCACGACA GGAGAGTGTCATTAAGTATGAACTGCTCTTCCGGGAGGGCGACCGAGGCCGAGAGGTGGGGCGAACCTTC GACCCAACCACAGCCTTTGTGGTGGAGGACCTCAAGCCCAATACGGAGTATGCGTTCCGGCTGGCGGCGC GCTCGCCGCAGGGCCTGGGCGCCTTCACCGCGGTCGTGCGCCAGCGCACGCTGCAGGCCAAACCGTCAGC CCCCCCTCAAGACGTTAAGTGCACCAGCTTGCGCTCCACGGCCATATTGGTAAGTTGGCGCCCGCCACCG CCAGAAACTCACAACGGGGCCCTCGTGGGCTACAGCGTCCGCTACCGACCGCTGGGCTCAGAGGACCCGG ACCCCAAGGAGGTGAACAACATACCCCCGACCACCACTCAGATCCTTCTGGAAGCTTTGGAGAAATGGAC GGAGTACCGTGTCACCGCCGTGGCTTACACAGAGGTGGGACCAGGGCCCGAGAGCTCGCCCGTGGTCGTC CGCACCGATGAGGACGTGCCCAGCGCGCCCCCGCGGAAGGTGGAGGCGGAGGCGCTCAACGCCACAGCCA TCCGAGTGCTGTGGCGCTCGCCCACGCCCGGCCGGCAGCACGGGCAGATCCGCGGCTACCAGGTCCACTA TGTGCGCATGGAGGGTGCCGAGGCCCGCGGGCCACCGCGCATCAAGGACATCATGCTGGCGGATGCCCAG GAAATGGTGATAACGAACCTCCAGCCTGAGACTGCTTACTCTATCACAGTAGCCGCGTATACCATGAAAG GCGATGGCGCTCGCAGCAAACCGAAGGTGGTGGTGACCAAGGGAGCAGTGCTGGGCCGCCCCACCCTGTC GGTGCAGCAGACCCCCGAGGGCAGCCTGCTGGCGCGCTGGGAGCCCCCCGCGGACGCGGCCGAGGACCCG GTGCTTGGCTACCGCCTGCAGTTTGGGCGCGAAGACGCGGCCCCGGCCACGTTGGAGCTGGCTGCGTGGG AGCGGCGGTTCGCGGCGCCTGCACACAAGGGCGCCACCTATGTGTTCCGGCTGGCAGCGCGGGGCCGCGC GGGGTTGGGCGAGGAGGCCGCGGCAGCGCTGAGCATCCCCGAGGACGCTCCGCGCGGCTTCCCGCAGATC TTGGGCGCCGCGGGCAACGTGTCCGCGGGCTCCGTGCTACTGCGCTGGCTGCCACCCGTGCCCGCCGAGC GCAACGGCGCCATCATCAAGTACACGGTGTCCGTGCGGGAGGCCGGCGCCCCTGGGCCCGCGACCGAGAC GGAGCTGGCGGCGGCCGCCCAGCCGGGGGCCGAGACAGCGCTCACGCTGCGAGGGCTGCGGCCGGAGACG GCCTACGAGTTACGCGTGCGCGCACACACGCGTCGCGGCCCGGGCCCCTTCTCACCCCCGCTGCGCTACA GGCTCGCGCGGGACCCAGTCTCCCCAAAGAACTTCAAGGTGAAGATGATCATGAAGACTTCAGTGCTGCT GAGCTGGGAGTTCCCCGACAACTATAACTCACCCACACCCTACAAGATTCAGTACAATGGGCTCACCCTG GATGTGGACGGCCGCACGACCAAGAAGCTGATCACACACCTCAAGCCACACACCTTCTATAATTTCGTGC TCACCAACCGTGGCAGCAGCCTGGGGGGCCTGCAGCAGACGGTCACTGCCAGGACCGCCTTTAACATGCT CAGTGGCAAGCCTAGCGTCGCCCCGAAGCCCGACAATGACGGTTTCATCGTGGTCTACCTGCCTGATGGC CAGAGTCCTGTGACCGTGCAGAACTACTTCATTGTGATGGTCCCACTTCGGAAGTCTCGAGGTGGCCAGT TCCCTGTCCTACTAGGTAGTCCAGAGGACATGGATCTGGAGGAGCTCATCCAGGACATCTCCCGGCTGCA GAGGCGCAGCCTGCGCCACTCCAGACAGCTGGAGGTGCCTCGGCCCTACATCGCCGCTCGATTCTCCATC CTGCCAGCTGTCTTCCATCCTGGGAACCAGAAGCAATATGGTGGCTTTGACAACAGGGGCTTGGAGCCAG GCCACCGCTATGTCCTCTTTGTGCTTGCTGTGTTGCAGAAGAATGAGCCTACATTTGCAGCCAGTCCCTT CTCAGACCCCTTCCAGCTGGACAACCCGGACCCTCAGCCCATTGTGGACGGCGAGGAGGGCCTCATCTGG GTGATTGGGCCTGTGCTGGCCGTGGTCTTCATCATCTGCATCGTGATTGCCATCCTGCTGTACAAGAACA AACCTGACAGCAAACGCAAGGACTCAGAGCCCCGCACCAAATGCTTACTGAACAATGCCGACCTTGCCCC CCATCACCCCAAGGACCCTGTGGAAATGCGACGCATCAACTTCCAGACACCAGGTATGCTCAGCCACCCA CCCATCCCCATCACAGACATGGCGGAGCACATGGAGAGACTCAAAGCCAACGACAGCCTGAAGCTCTCCC AGGAGTACGAGTCCATTGACCCCGGGCAGCAATTCACGTGGGAACATTCGAACCTGGAGGCCAACAAGCC CAAGAACCGCTATGCCAACGTCATCGCCTATGACCACTCACGAGTCATCCTGCAGCCCCTAGAAGGCATC ATGGGTAGTGATTACATCAATGCCAACTATGTGGACGGCTACCGGCGGCAGAATGCATACATTGCCACGC AGGGGCCCCTGCCTGAGACCTTTGGGGACTTCTGGCGGATGGTGTGGGAGCAGCGATCGGCCACTGTGGT CATGATGACGCGACTGGAGGAGAAATCACGGATCAAATGTGACCAATACTGGCCTAACCGAGGCACCGAG ACATACGGCTTCATCCAGGTCACCCTACTAGATACCATGGAGCTGGCTACCTTCTGCGTCAGGACTTTTT CTCTACACAAGAATGGCTCTAGCGAGAAGCGTGAGGTGCGACATTTCCAGTTCACGGCATGGCCCGACCA CGGGGTACCTGAGTACCCCACGCCCTTCCTGGCATTCCTGCGAAGAGTCAAGACCTGCAACCCGCCTGAT GCTGGCCCCATTGTGGTCCACTGCAGCGCGGGTGTGGGGCGCACTGGCTGCTTCATCGTAATTGACGCCA TGCTAGAGCGCATCAAGACAGAGAAGACCGTGGATGTGTATGGACATGTGACACTCATGCGGTCGCAGCG CAACTACATGGTGCAGACAGAGGATCAGTATGGCTTCATCCACGAGGCGCTGCTGGAGGCTGTGGGCTGC GGCAATACCGAGGTCCCTGCTCGCAGCCTCTACACCTACATCCAGAAGCTGGCCCAGGTGGAGCCTGGCG AGCACGTCACGGGCATGGAGCTTGAGTTCAAGAGGCTCGCCAGTTCCAAGGCACACACTTCGCGCTTCAT CACCGCCAGCCTGCCTTGCAACAAGTTTAAGAACCGACTGGTGAACATCCTGCCGTACGAGAGCTCGCGT GTCTGCCTGCAGCCCATCCGCGGTGTGGAGGGCTCTGACTACATCAATGCCAGCTTTATCGACGGCTATA GACAGCAGAAAGCCTACATTGCAACACAGGGGCCACTGGCAGAGACCACAGAGGACTTCTGGCGAGCTCT GTGGGAGAACAACTCTACTATTGTCGTAATGCTCACCAAGCTCCGAGAAATGGGCCGGGAAAAGTGCCAC CAGTACTGGCCAGCCGAGCGCTCTGCCCGCTACCAGTACTTTGTGGTTGACCCGATGGCAGAGTATAACA TGCCACAGTACATTCTGCGTGAGTTTAAGGTCACAGATGCCCGGGATGGCCAGTCCCGGACCGTCCGACA GTTCCAGTTCACGGACTGGCCAGAGCAGGGTGCACCCAAGTCAGGGGAAGGCTTCATTGACTTCATCGGC CAAGTGCATAAGACCAAGGAGCAGTTTGGCCAGGACGGACCCATCTCAGTGCACTGCAGCGCCGGAGTGG GCAGGACCGGAGTGTTCATCACCCTGAGCATCGTGCTTGAGCGGATGCGCTACGAGGGCGTGGTGGACAT TTTCCAGACAGTGAAGGTGCTTCGGACCCAGAGGCCTGCCATGGTGCAGACAGAGGACGAGTACCAGTTC TGCTTCCAGGCGGCTTTGGAATACCTGGGCAGTTTTGATCATTATGCAACA >MG222172 representing NM_011218
Red=Cloning site Green=Tags(s) MAPTWSPSVVSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKG KKVNSQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITIHAKLTVLREDQLPPGFPNIDMG PQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVAT NSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV GRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSYY VIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNV QARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLA FTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREVGRTF DPTTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPP PETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVV RTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQ EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPADAAEDP VLGYRLQFGREDAAPATLELAAWERRFAAPAHKGATYVFRLAARGRAGLGEEAAAALSIPEDAPRGFPQI LGAAGNVSAGSVLLRWLPPVPAERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLRGLRPET AYELRVRAHTRRGPGPFSPPLRYRLARDPVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTL DVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSVAPKPDNDGFIVVYLPDG QSPVTVQNYFIVMVPLRKSRGGQFPVLLGSPEDMDLEELIQDISRLQRRSLRHSRQLEVPRPYIAARFSI LPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKNEPTFAASPFSDPFQLDNPDPQPIVDGEEGLIW VIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHP PIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGI MGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRIKCDQYWPNRGTE TYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPD AGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGC GNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILPYESSR VCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCH QYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIG QVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQF CFQAALEYLGSFDHYAT |
Restriction Sites | Not Cloning Scheme for this gene |
ACCN | NM_011218 |
ORF Size | 5721 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_011218.2, NP_035348.2 |
RefSeq Size | 6874 bp |
RefSeq ORF | 5724 bp |
Locus ID | 19280 |
UniProt ID | B0V2N1 |
Gene Summary | Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans (PubMed:19833921, PubMed:21454754, PubMed:22406547). Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth (PubMed:21454754). Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection (PubMed:15797710, PubMed:19833921, PubMed:19780196, PubMed:21454754, PubMed:22519304, PubMed:22406547). Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2 (PubMed:21454754). Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb (PubMed:10080191). Functions as tyrosine phosphatase (PubMed:7529177). Mediates dephosphorylation of NTRK1, NTRK2 and NTRK3 (By similarity). Plays a role in down-regulation of signaling cascades that lead to the activation of Akt and MAP kinases (PubMed:15797710). Down-regulates TLR9-mediated activation of NF-kappa-B, as well as production of TNF, interferon alpha and interferon beta (PubMed:26231120).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |