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GPCR MRGX2 (MRGPRX2) (NM_054030) Human Tagged Lenti ORF Clone
CAT＃: RC209033L4
- LentiORF®
Lenti ORF clone of Human MAS-related GPR, member X2 (MRGPRX2), mGFP tagged
"NM_054030" in other vectors (4)
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CNY 4,800.00
CNY 5,890.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | mGFP |
| Synonyms | MGRG3; MRGX2 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC209033).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_054030 |
| ORF Size | 990 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_054030.2 |
| RefSeq Size | 2130 bp |
| RefSeq ORF | 993 bp |
| Locus ID | 117194 |
| UniProt ID | Q96LB1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| MW | 37.1 kDa |
| Gene Summary | Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209033 | MRGPRX2 (Myc-DDK-tagged)-Human MAS-related GPR, member X2 (MRGPRX2) |
CNY 2,400.00 |
|
| RC209033L3 | Lenti ORF clone of Human MAS-related GPR, member X2 (MRGPRX2), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RG209033 | MRGPRX2 (tGFP-tagged) - Human MAS-related GPR, member X2 (MRGPRX2) |
CNY 4,000.00 |
|
| SC120221 | MRGPRX2 (untagged)-Human MAS-related GPR, member X2 (MRGPRX2) |
CNY 2,400.00 |
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