Sigma1 receptor (SIGMAR1) (NM_005866) Human Untagged Clone
CAT#: SC111748
SIGMAR1 (untagged)-Human sigma non-opioid intracellular receptor 1 (SIGMAR1), transcript variant 1
CNY 2,400.00
CNY 2,950.00
Cited in 2 publications. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SR-BP; SR-BP1; SRBP |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_005866, RT-PCR generated
ATGCCGTGGGCCGTGGGCCGGCGGTGGGCGTGGGCCGCGCTGCTCCTGGCTGTCGCAGCG GTGCTGACCCAGGTCGTCTGGCTCTGGCTGGGTACGCAGAGCTTCGTCTTCCAGCGCGAA GAGATAGCGCAGTTGGCGCGGCAGTACGCTGGGCTGGACCACGAGCTGGCCTTCTCTCGT CTGATCGTGGAGCTGCGGCGGCTGCACCCAGGCCACGTGCTGCCCGACGAGGAGCTGCAG TGGGTGTTCGTGAATGCGGGTGGCTGGATGGGCGCCATGTGCCTTCTGCACGCCTCGCTG TCCGAGTATGTGCTGCTCTTCGGCACCGCCTTGGGCTCCCGCGGCCACTCGGGGCGCTAC TGGGCTGAGATCTCGGATACCATCATCTCTGGCACCTTCCACCAGTGGAGAGAGGGCACC ACCAAAAGTGAGGTCTTCTACCCAGGGGAGACGGTAGTACACGGGCCTGGTGAGGCAACA GCTGTGGAGTGGGGGCCAAACACATGGATGGTGGAGTACGGCCGGGGCGTCATCCCATCC ACCCTGGCCTTCGCGCTGGCCGACACTGTCTTCAGCACCCAGGACTTCCTCACCCTCTTC TATACTCTTCGCTCCTATGCTCGGGGCCTCCGGCTTGAGCTCACCACCTACCTCTTTGGC CAGGACCCTTGA >OriGene 5' read for NM_005866 unedited
GGCGAGCCTACAGTATTTGTAAACGACTCACGTCTGGCGGCCGCCACGTGTGATGGAATC TGCAGAATCGGCTTATGCCGTGGGCCGTGGGCCGGCGGTGGGCGTGGGCCGCGCTGCTCC TGGCTGTCGCAGCGGTGCTGACCCAGGTCGTCTGGCTCTGGCTGGGTACGCAGAGCTTCG TCTTCCAGCGCGAAGAGATAGCGCAGTTGGCGCGGTAGTACGCTGGGCTGGACCACGAGC TGGCGCTTCTCTCGTCTGATCGTGGAGCTGCGGCGGCTGCACCCAGGCCACGTGCTGCCC GACGAGGAGCTGCAATGGGTGTTCGTGAATGCGGGTGGCTGGATGGGCGCCATGTGCCTT CTGCACGCCTCGCTGTCCGAGTATGTGCTGCTCTTCGGCACCGCCTTGGGCTCCCGCGGC CACTCGGGGCGCTACTGGGCTGAGATCTCGGATACCATCATCTCTGGCACCTTCCACCAG TGGAGAGAGGGCACCACCAAAAGTGAGGTCTTCTACCCAGGGGAGACGGTAGTACACGGG CCTGGTGAGGCAACAGCTGTGGAGTGGGGGCCAAACACATGGATGGTGGAGTACGGCCGG GGCGTCATCCCATCCACCCTGGCCTTTGGGCTGGCCGACACTGTCTTCAGCACCCAGGAC TTCCTCACCCTCTTCTATACTCTTCGCTCCTATGCTCGGGGGCCTCCCGGCTGGAGCTCA CCACCTACCTCTTTGGCCAGGACCTTTGACCAGCCCAGAACCGAATTCCAACACAGTGGC GGCCGTTACTAGTGGGACCCGAGCTCTGTGCCCGATATCAAAGCTGGGCGACTCTAGATT GCGGCCCCGGTCATACCTGTTTTCTGGACAGATCCCGGGGTGCAATA |
Restriction Sites | Please inquire |
ACCN | NM_005866 |
Insert Size | 1700 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_005866.2, NP_005857.1 |
RefSeq Size | 1655 bp |
RefSeq ORF | 672 bp |
Locus ID | 10280 |
UniProt ID | Q99720 |
Domains | ERG2_Sigma1R |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Gene Summary | This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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The sigma 1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands
,Mishra, AK;Mavlyutov, TA;Singh, DR;Biener, G;Yang, J;Oliver, JA;Ruoho, AE;Raicu, V;,
Biochem. J.
,PubMed ID 25510962
[SIGMAR1]
|
Sigma-1 Receptor Enhances Neurite Elongation of Cerebellar Granule Neurons via TrkB Signaling
,Kimura, Y;Fujita, Y;Shibata, K;Mori, M;Yamashita, T;,
PLoS One. 2013 Sep 19;8(9):e74466
,PubMed ID 24116072
[SIGMAR1]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC201206 | SIGMAR1 (Myc-DDK-tagged)-Human sigma non-opioid intracellular receptor 1 (SIGMAR1), transcript variant 1 |
CNY 2,400.00 |
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RC201206L1 | Lenti ORF clone of Human sigma non-opioid intracellular receptor 1 (SIGMAR1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
RC201206L2 | Lenti ORF clone of Human sigma non-opioid intracellular receptor 1 (SIGMAR1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC201206L3 | Lenti ORF clone of Human sigma non-opioid intracellular receptor 1 (SIGMAR1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
RC201206L4 | Lenti ORF clone of Human sigma non-opioid intracellular receptor 1 (SIGMAR1), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
RG201206 | SIGMAR1 (tGFP-tagged) - Human sigma non-opioid intracellular receptor 1 (SIGMAR1), transcript variant 1 |
CNY 4,000.00 |
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