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SHTN1 (NM_018330) Human Untagged Clone
CAT＃: SC113549
KIAA1598 (untagged)-Human KIAA1598 (KIAA1598), transcript variant 2
CNY 7,320.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KIAA1598; shootin-1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_018330, the custom clone sequence may differ by one or more nucleotides
ATGAACAGCTCGGACGAAGAGAAGCAGCTGCAGCTCATTACCAGTCTGAAGGAGCAAGCAATAGGCGAAT ATGAAGACCTTAGAGCAGAGAACCAGAAAACAAAGGAGAAGTGTGACAAAATTAGGCAAGAACGAGATGA AGCCGTTAAAAAACTGGAAGAATTTCAGAAAATTTCTCACATGGTCATAGAGGAAGTTAATTTCATGCAG AACCATCTTGAAATAGAGAAGACTTGTCGAGAAAGTGCTGAAGCTTTGGCAACAAAGCTAAATAAAGAAA ATAAAACGTTGAAAAGAATCAGCATGTTGTACATGGCCAAGCTGGGACCAGATGTAATAACTGAAGAGAT AAACATTGATGATGAAGATTCGACTACAGACACAGACGGTGCCGCCGAGACTTGTGTCTCAGTACAGTGT CAGAAGCAAATTAAAGAACTTCGAGATCAAATTGTATCTGTTCAGGAGGAAAAGAAGATTTTAGCCATTG AGCTGGAAAATCTCAAGAGCAAACTCGTAGAAGTAATTGAAGAAGTAAATAAAGTTAAACAAGAAAAGAC TGTTTTAAATTCAGAAGTTCTTGAACAGAGAAAAGTCTTAGAAAAATGCAATAGAGTGTCCATGTTAGCT GTAGAAGAGTATGAGGAGATGCAAGTAAACCTGGAGCTGGAGAAGGACCTTCGAAAGAAAGCAGAGTCAT TTGCACAAGAGATGTTCATTGAGCAAAACAAGCTAAAGAGACAAAGCCACCTTCTGCTGCAGAGCTCCAT CCCTGATCAGCAGCTTTTGAAAGCTTTAGACGAAAATGCAAAACTCACCCAGCAACTTGAAGAAGAGAGA ATTCAGCATCAACAAAAGGTCAAAGAATTAGAAGAGCAACTAGAAAATGAAACACTCCACAAAGAAATAC ACAACCTCAAACAGCAACTGGAGCTTCTAGAGGAAGATAAAAAGGAATTGGAATTGAAATATCAGAATTC TGAAGAGAAAGCCAGAAATTTAAAGCACTCTGTTGATGAACTCCAGAAACGAGTGAACCAGTCTGAGAAT TCAGTACCTCCACCACCTCCTCCTCCACCACCACTTCCCCCTCCACCTCCCAATCCTATCCGATCCCTCA TGTCCATGATCCGGAAACGATCCCACCCCAGTGGCAGTGGTGCTAAGAAAGAAAAGGCAACTCAACCAGA AACAACTGAAGAAGTCACAGATCTAAAGAGGCAAGCAGTTGAAGAGATGATGGATAGAATTAAAAAGGGA GTTCATCTTAGACCCGTTAATCAGACAGCCAGACCGAAGACAAAGCCAGAATCTTCGAAAGGCTGCGAAA GTGCAGTGGATGAACTAAAAGGAATACTGGCCTCCCAGTAG >OriGene 5' read for NM_018330 unedited
NGTCGGAATTTGTATACGACTCATATAGGCGGCCGCGNATTCGGCACGAGGGGAATACAC AACCTCAAACAGCAACTGGAGCTTCTAGAGGAAGATAAAAAGGAATTGGAATTGAAATAT CAGAATTCTGAAGAGAAAGCCAGAAATTTAAAGCACTCTGTTGATGAACTCCAGAAACGA GTGAACCAGTCTGAGAATTCAGTACCTCCACCACCTCCTCCTCCACCACCACTTCCCCCT CCACCTCCCAATCCTATCCGATCCCTCATGTCCATGATCCGGAAACGATCCCACCCCAGT GGCAGTGGTGCTAAGAAAGAAAAGGCAACTCAACCAGAAACAACTGAAGAAGTCACAGAT CTAAAGAGGCAAGCAGTTGAAGAGATGATGGATAGAATTAAAAAGGGAGTTCATCTTAGA CCCGTTAATCAGACAGCCAGACCGAAGACAAAGCCAGAATCTTCGAAAGGCTGCGAAAGT GCAGTGGATGAACTAAAAGGAATACTGGGGACACTTAACAAATCCACTAGTTCAAGAAGC TTAAAATCCCTTGACCCTGAAAACAGTGAAACTGAGTTAGAAAGGATTTTGCGTCGCAGA AAGGTGACAGCAGAAGCAGATAGCAGTAGTCCAACTGGGATATTAGCCACCTCAGAGTCC AAATCCATGCCAGTGTTGGGTTCTGTATCCAGTGTAACAAAAACAGCCTTGAACAAGAAA CTCTGGAGGCAGAATTCAACAGCCCGTNCCCCCCAACACCTGAGCCAGGTGAAAGGCCCC GTANATTGGAAGGATGCACAAGTTTCAAGGTTACGTTTCAGCCTCCAGTAGCATTGGATG CAGGAAAAATACATTGACGGTGAAAACAGCCGAACAGNTGTAGTTTTAGACCTGTTTTAC ACTGAACCCAACC >OriGene 3' read for NM_018330 unedited
CGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGGAAATATTGGTGCCTTTTT AATAAGTTGTGGTGAGGAGAGTTCAAATTACAGCATAACAGAATTCGTTTCGTGAATTAA TGCAGTCTGTAGTAAGCATATCATATAGCAGTATTATCCAGTTAAAGAAAGATACAGTTG AAAAACATTACGTTTTAATTCTCCATGAGTAAAGTGATAAGTAACTATAAAATCATTATT GGGAGAACATGGAAACAGTCAAGCATAACGAACTTACAGAAAGATAATTATCTCCAAATT TAGGAAGTACATGTACCTGCCTACCCACCTCTTCAAGCCTATGCTTACCACACGTGCAAA AATACAATACAATACAACTACTGCAATTATTACTATCATTTTCTTTTGCCCTTAGGTGAA AAACACCTGACAGCTACATGCTGAGCCATGCTAACAAAACTAAACCTTTCACTTTCTTTA ATAGTAAAATTACCATTACTGAATCATTGTCATAAAAAGTGCATTCAAGTACATTACCAC TTATTTTAAATAAACACCAATTTTGAAACAATCAACTTTGAAAAGCTGCATAAGTTTTTT TTTTAATCCCTGATTACATTTCTATTTATTCACTGTGGTAGCCTGAAACATTGTATTTTT AGAGACTAACTACTGCTTAATTTCTTTTTTAAAAAAAACAACAACAAACCTGTGTAATAT AGAACAGCAGTGAAGCAAGAANAATGTGTGCTTGTCACTTATCTTCACCATACTGTACAT AAGAACTCTGATAAATATGGTACTTGTGCCACATAGTATTTGGGAAAACATANTNACTCA TGCACAGAGCCATGGGTTACCNACTACTACTGTAAAATCAGGGTNGGACTTTACCTCAGT CTGGATTCAGCTACAGAGCATCCACGGAGGCCTCGGNAGCTTGGNACCATCAAGCTGNAT TTTCACCATAGTAACAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_018330 |
| Insert Size | 2790 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_018330.2, NP_060800.1 |
| RefSeq Size | 5047 bp |
| RefSeq ORF | 378 bp |
| Locus ID | 57698 |
| UniProt ID | A0MZ66 |
| Gene Summary | Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth. Mediates netrin-1-induced F-actin-substrate coupling or 'clutch engagement' within the axon growth cone through activation of CDC42, RAC1 and PAK1-dependent signaling pathway, thereby converting the F-actin retrograde flow into traction forces, concomitantly with filopodium extension and axon outgrowth. Plays a role in cytoskeletal organization by regulating the subcellular localization of phosphoinositide 3-kinase (PI3K) activity at the axonal growth cone. Plays also a role in regenerative neurite outgrowth. In the developing cortex, cooperates with KIF20B to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in the accumulation of phosphatidylinositol 3,4,5-trisphosphate (PIP3) in the growth cone of primary hippocampal neurons.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks two consecutive exons in the 3' coding region compared to variant 1, which results in a frame-shift and a shorter isoform (b, also known as shootin 1a) with a distinct C-terminus compared to isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223326 | KIAA1598 (Myc-DDK-tagged)-Human KIAA1598 (KIAA1598), transcript variant 2 |
CNY 3,656.00 |
|
| RC223326L3 | Lenti ORF clone of Human KIAA1598 (KIAA1598), transcript variant 2, Myc-DDK-tagged |
CNY 5,990.00 |
|
| RC223326L4 | Lenti ORF clone of Human KIAA1598 (KIAA1598), transcript variant 2, mGFP tagged |
CNY 5,990.00 |
|
| RG223326 | KIAA1598 (tGFP-tagged) - Human KIAA1598 (KIAA1598), transcript variant 2 |
CNY 4,470.00 |
|
| SC317750 | KIAA1598 (untagged)-Human KIAA1598 (KIAA1598), transcript variant 2 |
CNY 7,320.00 |
