TLL1 (BC016922) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	TLL; tolloid-like 1
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC016922 edited GACCCACGCGTCCGGTCCCGGCGGCATCCACATGTTTCCGGACACCTGAGCACCCCGGTC CCGCCGAGGAGCCTCCGGGTGGGGAGAAGAGCACCGGTGCCCCTAGCCCCGCACATCAGC GCGGACCGCGGCTGCCTAACCTCTGGGTCCCGTCCCCTCCTTTTCCTCCGGGGGAGGAGG ATGGGGTTGGGAACGCTTTCCCCGAGGATGCTCGTGTGGCTGGTGGCCTCGGGGATTGTT TTCTACGGGGAGCTATGGGTCTGCGCTGGCCTCGATTATGATTACACTTTTGATGGGAAC GAAGAGGATAAAACAGAGACTATAGATTACAAGGACCCGTGTAAAGCCGCTGTATTTTGG GGCGATATTGCCTTAGATGATGAAGACTTAAATATCTTTCAAATAGATAGGACAATTGAC CTTACGCAGAACCCCTTTGGAAACCTTGGACATACCACAGGTGGACTTGGAGACCATGCT ATGTCAAAGAAGCGAGGGGCCCTCTACCAACTTATAGACAGGATAAGAAGAATTGGCTTT GGCTTGGAGCAAAACAACACAGTTAAGGGAAAAGTACCTCTACAATTCTCAGGGCAAAAT GAGAAAAATCGAGTTCCCAGAGCCGCTACATCAAGAACGGAAAGAATATGGCCTGGAGGC GTTATTCCTTATGTTATAGGAGGAAACTTCACTGGCAGCCAGAGAGCCATGTTCAAGCAG GCCATGAGGCACTGGGAAAAGCACACATGTGTGACTTTCATAGAAAGAAGTGATGAAGAG AGTTACATTGTATTCACCTATAGGCCTTGTGGATGCTGCTCCTATGTAGGTCGGCGAGGA AATGGACCTCAGGCAATCTCTATCGGCAAGAACTGTGATAAATTTGGGATTGTTGTTCAT GAATTGGGTCATGTGATAGGCTTTTGGCATGAACACACAAGACCAGATCGAGATAACCAC GTAACTATCATAAGAGAAAACATCCAGCCAGGTCAAGAGTACAATTTTCTGAAGATGGAG CCTGGAGAAGTAAACTCACTTGGAGAAAGATATGATTTCGACAGTATCATGCACTATGCC AGGAACACCTTCTCAAGGGGGATGTTTCTGGATACCATTCTCCCCTCCCGTGATGATAAT GGCATACGTCCTGCAATTGGTCAGCGAACCCGTCTAAGCAAAGGAGATATCGCACAGGCA AGAAAGCTGTATAGATGTCCAGCATGTGGAGAAACTCTACAAGAATCCAATGGCAACCTT TCCTCTCCAGGATTTCCCAATGGCTACCCTTCTTACACACACTGCATCTGGAGAGTTTCT GTGACCCCAGGGGAGAAGGTTGTATTTTCACTCTGTTGATTGTGTCTTCTGATGAACACA AATTATAAAGTTTGATGTCATACCACTTGTCTACTTTTAGTTTTATTGCCTGTGCTTTTG GTGTCATAGCCAAGAAATCATGGCCATATGTAATGACATGAAGTTTTTACCCTGTGTTTT CTTCTATGAGTTCTATAGTTTTACAGTCTTATATGTAGGTTTTTAATCAATATTGTGTTA ATAGAAACCATTCTTGTACATGTGGATATCCAGTTTCTTCAACACCATTTGTTAAAGATT TACTAAATGTTTTTATTCAGCATTCCTGCTCATGTTTCTGACTTCTATTATGGCTTATTT TGGTCCTGCCTATAGCTTACATTATAGATTATTTTTTAAATTAGCGTTTTTGTTTTTTTC TGTTTGAAAATGTGGATTTTTTACATGAATTTATAAAACTATAGTTTCACTGGATATAGT TGGCTGCACATTTAACTTTGTTTTAAATAAAAGCTTGCAAAAATAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC016922 unedited NGCGATGGGATTTGTATACGACTTTTATAGGCGGCCGCAGATTCCCGGGATATCGTCGAC CCACGCGTCCGGACCCACGCGTCCGGTCCCGGCGGCATCCACATGTTTCCGGACACCTGA GCACCCCGGTCCCGCCGAGGAGCCTCCGGGTGGGGAGAAGAGCACCGGTGCCCCTAGCCC CGCACATCAGCGCGGACCGCGGCTGCCTAACCTCTGGGTCCCGTCCCCTCCTTTTCCTCC GGGGGAGGAGGATGGGGTTGGGAACGCTTTCCCCGAGGATGCTCGTGTGGCTGGTGGCCT CGGGGATTGTTTTCTACGGGGAGCTATGGGTCTGCGCTGGCCTCGATTATGATTACACTT TTGATGGGAACGAAGAGGATAAAACAGAGACTATAGATTACAAGGACCCGTGTAAAGCCG CTGTATTTTGGGGCGATATTGCCTTAGATGATGAAGACTTAAATATCTTTCAAATAGATA GGACAATTGACCTTACGCAGAACCCCTTTGGAAACCTTGGACATACCACAGGTGGACTTG GAGACCATGCTATGTCAAAGAAGCGAGGGGCCCTCTACCAACTTATAGACAGGATAAGAA GAATTGGCTTTGGCTTGGAGCAAAACAACACAGTTAAGGGAAAAGTACCTCTACAATTCT CAGGGCAAAATGAGAAAAATCGAGTTCCCAGAGCCGCTACATCAAGAACGGAAAGAATAT GGCCTGGAGGCGTTATTCCTTATGTTATAGGAGGAAACTTCACTGGCAGCCAGAGAGCCA TGTTCAAGCANNGCCATGAGCACTGGGAAAGCACACATGTGTGACTTTNCATAGAAGAAG TGATGAAGAGAGTTACATTGTATTCACCTATAGGCCCTTNGGGATGCTGCTCCTATGTAG GTCGGCGAGGAAATGA
Restriction Sites	Please inquire
ACCN	BC016922
Insert Size	1887 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC016922.1, AAH16922.1
RefSeq Size	1887 bp
Locus ID	7092
Protein Families	Druggable Genome, Protease, Secreted Protein
Gene Summary	This gene encodes an astacin-like, zinc-dependent, metalloprotease that belongs to the peptidase M12A family. This protease processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Studies in mice suggest that this gene plays multiple roles in the development of mammalian heart, and is essential for the formation of the interventricular septum. Allelic variants of this gene are associated with atrial septal defect type 6. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

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