C19orf46 (SYNE4) (BC052573) Human Untagged Clone
CAT#: SC126277
C19orf46 (untagged)-Human hypothetical protein FLJ36445, mRNA (cDNA clone MGC:60006 IMAGE:6568945), complete cds
CNY 2,400.00
CNY 2,950.00
货期*
现货
规格
Cited in 1 publication. |
Product images
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经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | FLJ36445 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for BC052573 edited
TTCGGCACGAGGCTCCAGCGGAGGAGCTCTGGGACACCCTTGTCTAGGGAAGAGGTCTTA CTGGCTGCCCTCACCTGACTTTGTGTCCCCAGGCCCCCAGCCATGGCCCTGTCCCTGCCT CTGGGCCCTAGACTTGGCTCAGAGCCCCTCAACCACCCACCGGGAGCACCTAGAGAGGCG GACATTGTTGGATGCACCGTCTGCCCCGCGTCCGGAGAGGAGAGCACGAGCCCAGAGCAG GCCCAGACCCTGGGACAGGACTCCTTGGGCCCTCCTGAGCACTTCCAGGGTGGGCCAAGG GGCAATGAGCCTGCCGCTCACCCCCCGAGATGGTCAACACCCTCTTCCTACGAGGACCCA GCTGGGGGCAAACACTGTGAGGTGTTCGAGGAGGCCAACACGCTGGACCAGGACTTGGAG GTCGAGGGAGACTCGGACTGGCCAGGACCTGGTGGGGTCTGGGGGCCCTGGGCACCCAGT AGCCTCCCCACTTCCACAGAGTTGGAGTGGGATCCGGCGGGGGACATTGGGGGCCTTGGG CCCTTGGGACAAAAGACAGCCCGGACACTAGGAGTGCCCTGTGAGCTGTGTGGCCACAGG GGGCCCCAGGGCAGGGGACAAGGCCTTGAGGAAGCAGACACCTCTCACTCCCGACAGGAC ATGCTGGAGTCTGGCCTCGGCCACCAGAAACGCTTAGCACGTCACCAAAGACACTCCCTG CTCCGGAAGCCTCAGGACAAGAAGAGGCAAGCATCTCCTCATCTCCAGGATGTGAGGCTG GAGGGGAATCCAGGGGCCCCCGATCCTGCATCCAGGCAGCCTCTGACCTTCCTCCTTATC CTCTTCCTCCTCTTCCTCCTCCTGGTGGGTGCCATGTTTCTCCTGCCCGCGTCAGGAGGC CCCTGCTGCTCTCATGCCCGAATACCCAGGACACCCTACCTGGTGCTCAGCTATGTCAAT GGTCTTCCCCCAGTCTGATGTGTGTAATAAATGGTCACTGTCAAAAAAAAAAAAAAAAAA AAAAAA >OriGene 5' read for BC052573 unedited
NGGTTCAGATTTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGCTCCAG CGGAGGAGCTCTGGGACACCCTTGGGTAGGGAAGAGGTCTTACTGGCTGCCCTCACCTGA CTTTGTGTCCCCAGGCCCCCAGCCATGGCCCTGTCCCTGCCTCTGGGCCCTAGACTTGGC TCAGAGCCCCTCAACCACCCACCGGGAGCACCTAGAGAGGCGGACATTGTTGGATGCACC GTCTGCCCCGCGTCCGGAGAGGAGAGCACGAGCCCAGAGCAGGCCCAGACCCTGGGACAG GACTCCTTGGGCCCTCCTGAGCACTTCCAGGGTGGGCCAAGGGGCAATGAGCCTGCCGCT CACCCCCCGAGATGGTCAACACCCTCTTCCTACGAGGACCCAGCTGGGGGCAAACACTGT GAGGTGTTCGAGGAGGCCAACACGCTGGACCAGGACTTGGAGGTCGAGGGAGACTCGGAC TGGCCAGGACCTGGTGGGGTCTGGGGGCCCTGGGCACCCAGTAGCCTCCCCACTTCCACA GAGTTGGAGTGGGATCCGGCGGGGGACATTGGGGGCCTTGGGCCCTTGGGACAAAAGACA GCCCGGACACTANGAGTGCCCTGTGAGCTGTGTGGCCACAGGGGGCCCCANGGCAGGGGA CAAGGCCTTGAGGAAGCAGACACCTCTCACTCCCGACAGGACATGCTGGAGTCTGGCCTC NGCCACCANAAACGCTTAGCACGTCACCAAAGACACTCCCTGCTCCCGGAGCCTCAGGAC AAGAGAGGCAAGCATCTCCTCATCTCCAGGATGTGAGGCTGGAGGGGAATCCAGGGGCCC CCGATCCTGCATNCAGGCAGCCTCTGACCTTCCTCCTATNCTCTTNCTCCTCTTCCTCCC CTGGGGGGGGCCATGTTTCTCCTGCCCCGTCAGGAGGC |
Restriction Sites | Please inquire |
ACCN | BC052573 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | BC052573.1, AAH52573.1 |
RefSeq Size | 1026 bp |
RefSeq ORF | 873 bp |
Locus ID | 163183 |
Protein Families | Transmembrane |
Gene Summary | This gene is a member of the nesprin family of genes, that encode KASH (Klarsicht, Anc-1, Syne Homology) domain-containing proteins. In addition to the KASH domain, this protein also contains a coiled-coil and leucine zipper region, a spectrin repeat, and a kinesin-1 binding region. This protein localizes to the outer nuclear membrane, and is part of the linker of nucleoskeleton and cytoskeleton (LINC) complex in the nuclear envelope. LINC complexes are formed by SUN (Sad1, UNC-84)-KASH pairs, and are thought to mechanically couple nuclear components to the cytoskeleton. Mutations in this gene have been associated with progressive high-frequency hearing loss. The absence of this protein in mice also caused hearing loss, and changes in hair cell morphology in the ears. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
---|
The SUN protein UNC-84 is required only in force-bearing cells to maintain nuclear envelope architecture
,Cain, NE;Tapley, EC;McDonald, KL;Cain, BM;Starr, DA;,
J. Cell Biol. July 2014
,PubMed ID 25023515
[C19orf46]
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