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ERO1LB (ERO1B) (NM_019891) Human Untagged Clone
CAT＃: SC128104
ERO1LB (untagged)-Human ERO1-like beta (S. cerevisiae) (ERO1LB)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Ero1beta; ERO1LB |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128104 sequence for NM_019891 edited (data generated by NextGen Sequencing)
ATGAGCCAAGGGGTCCGCCGGGCAGGCGCTGGGCAGGGGGTAGCGGCCGCGGTGCAGCTG CTGGTCACCCTGAGCTTCCTGCGGAGCGTCGTCGAGGCGCAGGTCACTGGAGTTCTGGAT GATTGCTTGTGTGATATTGACAGCATCGATAACTTCAATACCTACAAAATCTTCCCCAAA ATAAAAAAATTGCAAGAGAGAGACTATTTTCGTTATTACAAGGTTAATCTGAAGCGACCT TGTCCTTTCTGGGCAGAAGATGGCCACTGTTCAATAAAAGACTGTCATGTGGAGCCCTGT CCAGAGAGTAAAATTCCGGTTGGAATAAAAGCTGGGCATTCTAATAAGTACTTGAAAATG GCAAACAATACCAAAGAATTAGAAGATTGTGAGCAAGCTAATAAACTGGGAGCAATTAAC AGCACATTAAGTAATCAAAGCAAAGAAGCTTTCATTGACTGGGCAAGATATGATGATTCA CGGGATCACTTTTGTGAACTTGATGATGAGAGATCTCCAGCTGCTCAGTATGTAGACCTA TTGCTGAACCCAGAGCGTTACACTGGCTATAAAGGGACCTCTGCATGGAGAGTGTGGAAC AGCATCTATGAAGAGAACTGTTTCAAGCCTCGATCTGTTTATCGTCCTTTAAATCCTCTG GCGCCTAGCCGAGGCGAAGATGATGGAGAATCATTCTACACATGGCTAGAAGGTTTGTGT CTGGAGAAAAGAGTCTTCTATAAGCTTATATCGGGACTTCATGCTAGCATCAATTTACAT CTATGCGCAAATTATCTTTTGGAAGAAACCTGGGGTAAGCCCAGTTGGGGACCTAATATT AAAGAATTCAAACACCGCTTTGACCCTGTGGAAACCAAGGGAGAAGGTCCAAGAAGGCTC AAGAATCTTTACTTTTTATACTTGATTGAGCTTCGAGCTTTGTCAAAGGTGGCTCCATAT TTTGAGCGCTCAATTGTCGATCTTTACACTGGAAATGCAGAAGAAGATGCTGACACAAAA ACTCTTCTACTGAATATCTTTCAAGATACAAAGTCCTTTCCCATGCACTTTGATGAGAAA TCCATGTTTGCAGGTGACAAAAAAGGGGCCAAGTCACTAAAGGAGGAATTCCGATTACAT TTCAAGAATATCTCCCGTATAATGGACTGTGTTGGATGTGACAAATGCAGATTATGGGGA AAATTACAGACTCAGGGTTTAGGAACTGCCCTGAAGATATTATTCTCTGAAAAAGAAATC CAAAAGCTTCCAGAGAATAGTCCATCTAAAGGCTTCCAACTCACCCGACAGGAAATAGTT GCTCTTTTAAATGCTTTTGGAAGGCTTTCTACAAGTATAAGAGACTTACAGAATTTTAAA GTCTTATTACAACAGAGTAGGTAA Clone variation with respect to NM_019891.3 1395 c=>g >OriGene 5' read for NM_019891 unedited
TTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGAAAGAGTCGCCTGCCT CCGGACCGGAGTGCAGACCTCTGACCCTGGAGTCGCTCGGCCGCTGGGAACCGTCCCCTT GGGTCGTCGCCTGGGCCGCCCGTCGTTCCCCGGCCCCGAGGGGTCCGGCTGGCCGCGGTG TGGGTAGAGGTCAGCATGAGCCAAGGGGTCCGCCGGGCAGGCGCTGGGCAGGGGGTAGCG GCCGCGGTGCAGCTGCTGGTCACCCTGAGCTTCCTGCGGAGCGTCGTCGAGGCGCAGGTC ACTGGAGTTCTGGATGAATTGCTTGTGTGATATTGACAGCATCGATAACTTCAATACCTA CAAAATCTTCCCCAAAATAAAAAAATTGCAAGAGAGAGACTATTTTCGTTATTACAAGGT TAATCTGAAGCGACCTTGTCCTTTCTGGGCAGAAGATGGCCACTGTTCAATAAAAGACTG TCATGTGGAGCCCTGTCCAGAGAGTAAAATTCCGGTTGGAATAAAAGCTGGGCATTCTAA TAAGTACTTGAAAATGGCAAACAATACCAAAGAATTAGAAGAATGTGAGCAAGCTAATAA ACTGGGAGCAATTAACAGCACATTAAGTAATCAAAGCAAAGAAGCTTTCATTGACTGGGC AAGATATGATGATTCACCGGGATCACTTTTTGTGAACTTGATATGGAGAGATCTNCAGCT GCTCAGTATGTAGACCTATTGCTGACCCCAGACGTTACACTGCTATANAGGGACTCTGCT GGGAGAGTGTGGACAGCATCTATAAGAGAATGNTAAGATGAAGGGGGGGGGGGGGAAAAA AAGAATTTTTTAAGGTTGGGAAGAACCGCCTCTTTTTTG >OriGene 3' genomic read for NM_019891 unedited
NCNGCCTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCAAAAACAGTACTTTAAT TCACATTTTCTAGATTCTGGGGGGTACAACAGTAAATTATTTGGAATTCTGTTCAAAATC AAAGCTGCCCCTGTAGATATTCCTTAAAATACAGTACACATAGATTTGTGGGGGTGTTTT TTTACCAAATAATTTCCACGATACCATGCACCTAATCTTGTATTTTGGTGAGTAGCTATG GTTTCTGCAGGTACCTCAGTTTGCAAACTACTGAGAGGTTTACTGGGAACTGTTCCCAAA TTTTCAGCTGAAGGCAATGCTGATGAAAATCCAAATAGCTGTCCTTTCTTATATACAGTG GCACATAGGCAAAGTTGAAAAACATGGCAGAGTTTCATATACCTAGATTACAAATATCGA ATAATTCACAATGTTAAAAATGTCAAAATAAAACGTTTTGACTTATCAAATTTCAAAAGT GTGGAGTCCTATTCTGGCTGATCCTCCTCATAATCCAAGAATCAAAACAGGAGAAACCTT CCAAGTTTACCAATTTTAATATATAGTTTGTCCAACTTACATAGATGCCACTTTAGTAAA AAATAAACCTACGCCCCTGGAAGAAGGGAAATTTTCCCTTTTCCTCCATTTCATAACTTC ACCCGTGGGTACCATCATTTCTGTCCGTTAAATTAACCAAGGGCTGGGTTTTAAAATTAG GGGAAGAGAAAAAGACCAAAATGCCCCAACCCCCGCCAAGCCTTTTTAAAAGGCAAAACA GTCCTCCAGTTAAAAACACCCTCCCAACAAAAGAGTTGAATTGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_019891 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_019891.2, NP_063944.2 |
| RefSeq Size | 2977 bp |
| RefSeq ORF | 1404 bp |
| Locus ID | 56605 |
| UniProt ID | Q86YB8 |
| Domains | ERO1 |
| Gene Summary | Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208445 | ERO1LB (Myc-DDK-tagged)-Human ERO1-like beta (S. cerevisiae) (ERO1LB) |
CNY 3,656.00 |
|
| RC208445L1 | Lenti ORF clone of Human ERO1-like beta (S. cerevisiae) (ERO1LB), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC208445L2 | Lenti ORF clone of Human ERO1-like beta (S. cerevisiae) (ERO1LB), mGFP tagged |
CNY 5,890.00 |
|
| RC208445L3 | Lenti ORF clone of Human ERO1-like beta (S. cerevisiae) (ERO1LB), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208445L4 | Lenti ORF clone of Human ERO1-like beta (S. cerevisiae) (ERO1LB), mGFP tagged |
CNY 5,890.00 |
|
| RG208445 | ERO1LB (tGFP-tagged) - Human ERO1-like beta (S. cerevisiae) (ERO1LB) |
CNY 5,256.00 |
