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DRG1 (NM_004147) Human Untagged Clone
CAT＃: SC321213
DRG1 (untagged)-Human developmentally regulated GTP binding protein 1 (DRG1)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NEDD3 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_004147.3
GGTGGCGGTGGCAGTTTGCCCGCGGGTGTGTGAAGGGAGACAGTGTGGAGGCCACAGGGT
ACTCGCCACGATGAGCAGCACCTTAGCTAAGATCGCGGAGATAGAAGCAGAGATGGCTCG GACTCAAAAGAACAAGGCCACAGCACACCACTTAGGGCTGCTTAAGGCTCGTCTTGCTAA GCTTCGTCGAGAACTCATTACTCCAAAGGGTGGTGGTGGTGGAGGTCCAGGAGAAGGTTT TGATGTGGCCAAGACAGGTGATGCTCGAATTGGATTTGTTGGTTTTCCATCTGTGGGGAA GTCAACACTGCTTAGTAACCTGGCAGGGGTATATTCTGAGGTGGCAGCCTATGAATTCAC TACTCTGACCACTGTGCCTGGTGTCATCAGATACAAAGGTGCCAAGATCCAGCTCCTGGA TCTCCCAGGTATCATTGAAGGTGCCAAGGATGGGAAAGGTAGAGGTCGTCAAGTCATTGC AGTGGCCCGAACCTGTAACTTGATCTTGATTGTTCTGGATGTCCTGAAACCTTTGGGACA TAAGAAGATAATTGAAAATGAGCTGGAAGGCTTTGGCATTCGCTTGAACAGCAAACCCCC CAACATTGGCTTTAAGAAGAAGGACAAGGGAGGCATTAATCTCACAGCCACTTGCCCCCA GAGTGAGCTGGATGCTGAAACTGTGAAGAGCATTCTGGCTGAATACAAGATTCATAATGC CGATGTGACTCTACGTAGTGATGCTACAGCTGATGACCTCATTGATGTGGTGGAAGGAAA CAGAGTTTATATCCCCTGTATCTATGTGTTAAATAAGATTGACCAAATCTCCATTGAGGA ATTGGATATCATCTATAAGGTGCCTCACTGTGTACCCATCTCTGCCCATCACCGCTGGAA TTTTGATGACCTATTGGAAAAGATCTGGGACTATCTGAAACTAGTGAGAATTTACACCAA ACCCAAAGGCCAGTTACCAGATTACACATCCCCAGTGGTGCTTCCTTACTCCAGGACCAC AGTGGAGGATTTCTGCATGAAGATTCACAAAAATCTTATCAAAGAATTTAAATATGCTCT GGTCTGGGGTCTCTCTGTGAAACACAATCCTCAGAAAGTGGGTAAAGACCATACGTTGGA GGATGAGGATGTCATTCAAATTGTGAAGAAGTGAAACCTTTCCCTTTTCCCATCTGCCGG ACGAACCACAACAGCGTTCCCCATGATCAAGCACCCTACCCCAGTTCTTTCTGGTTTTGG CAGTCACTGGATCAGGATCCAGGGGAGGGAGATGGAGGCACCCAAACTGGAACTTCATTT GTCTTACCTTGGTGTCACCTTGTATGTCGAACTGCATAAAAGATCTGGTAGGCTGGTCAG CTACATGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_004147 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004147.3, NP_004138.1 |
| RefSeq Size | 1467 bp |
| RefSeq ORF | 1104 bp |
| Locus ID | 4733 |
| UniProt ID | Q9Y295 |
| Domains | TGS, GTP1_OBG |
| Protein Families | Transcription Factors |
| Gene Summary | Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (PubMed:29915238, PubMed:23711155). Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions (PubMed:23711155). When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation (PubMed:19819225, PubMed:29915238). Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions (PubMed:28855639).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201259 | DRG1 (Myc-DDK-tagged)-Human developmentally regulated GTP binding protein 1 (DRG1) |
CNY 3,656.00 |
|
| RC201259L3 | Lenti ORF clone of Human developmentally regulated GTP binding protein 1 (DRG1), Myc-DDK-tagged |
CNY 5,890.00 |
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| RC201259L4 | Lenti ORF clone of Human developmentally regulated GTP binding protein 1 (DRG1), mGFP tagged |
CNY 5,890.00 |
|
| RG201259 | DRG1 (tGFP-tagged) - Human developmentally regulated GTP binding protein 1 (DRG1) |
CNY 5,256.00 |
