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TTI1 (NM_014657) Human Untagged Clone
CAT＃: SC324266
TTI1 (untagged)-Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1)
CNY 7,592.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KIAA0406; smg-10 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_014657.1
GAGAGTGAGAGAAAGGCTGGAAGACGAGACCTGCTCACTCTGTCACCGAGGCTAGAGTAC
AGTGGCACAATCACAGCTCATTGCAGCCTCAACCTCCCAGGCTCAATCGATCCTTCCAAC TGAGCCTCCCTAGCAGCTGGGACTATTAGTGCACACCACCACACCTAGCCTGCAGGATGT TTCCTCAATGAGGGGAAGGCTGCTGCACAATGGCAGTTTTTGATACTCCTGAGGAGGCCT TTGGTGTCTTACGTCCAGTCTGTGTTCAGCTCACAAAGACCCAGACAGTGGAGAATGTGG AGCATCTGCAGACACGACTACAAGCTGTGAGTGACAGTGCCCTTCAGGAACTTCAGCAGT ACATCCTCTTCCCTCTGCGATTTACCCTGAAGACCCCAGGTCCCAAAAGAGAGCGTTTGA TCCAAAGTGTGGTGGAATGCCTCACATTTGTCCTTTCTTCAACATGTGTGAAAGAACAGG AGCTTCTCCAGGAACTCTTTTCAGAACTCTCTGCTTGTCTGTATTCACCCAGCTCCCAAA AACCTGCGGCTGTGTCCGAGGAGTTGAAATTGGCTGTGATCCAGGGACTTAGCACATTAA TGCACTCAGCTTATGGGGACATCATTCTGACTTTTTATGAGCCCTCCATTCTGCCACGTT TAGGATTTGCTGTATCTTTACTGTTAGGCCTTGCAGAACAGGAGAAATCAAAGCAAATTA AAATTGCTGCCTTAAAATGTTTACAGGTTCTACTCTTGCAGTGTGATTGTCAGGACCATC CAAGGTCATTGGATGAACTTGAACAAAAGCAGCTGGGGGATTTGTTTGCCTCTTTTTTAC CTGGAATCTCAACTGCACTGACCAGGCTTATCACAGGAGACTTTAAACAAGGTCACAGCA TTGTCGTATCTTCCCTAAAGATCTTTTACAAGACAGTGAGCTTCATTATGGCTGATGAAC AGCTCAAAAGAATCTCAAAGGTCCAAGCAAAACCTGCAGTTGAGCACAGAGTAGCAGAGC TGATGGTTTACAGGGAAGCAGATTGGGTAAAAAAGACTGGCGACAAGTTGACTATCCTTA TTAAAAAGATAATTGAGTGTGTTTCTGTTCACCCACACTGGAAGGTGAGACTGGAACTGG TAGAACTTGTGGAGGACCTTCTTTTGAAGTGCAGTCAATCATTGGTCGAATGTGCTGGTC CCCTTCTGAAGGCCTTAGTGGGACTAGTAAATGATGAGAGTCCTGAAATCCAAGCCCAGT GCAATAAAGTTCTGAGACATTTTGCAGATCAAAAAGTAGTGGTGGGCAACAAAGCCCTCG CTGACATCTTGTCAGAAAGCCTGCATTCCCTTGCCACATCTCTTCCTCGCCTAATGAACT CCCAAGATGACCAGGGCAAATTCTCTACTCTTTCCTTGTTACTTGGTTATCTGAAACTCT TGGGCCCAAAAATAAACTTTGTCCTCAACTCTGTGGCCCATCTCCAGCGGCTTTCCAAAG CACTCATCCAAGTTCTAGAGCTAGACGTGGCTGACATCAAGATTGTTGAGGAACGGCGTT GGAACTCTGATGATCTGAATGCTTCTCCAAAGACCTCAGCCACACAGCCTTGGAACCGCA TCCAGAGGAGATATTTCCGCTTCTTCACTGATGAGAGAATCTTCATGCTCTTGAGGCAGG TTTGTCAGCTACTTGGTTATTATGGGAATCTTTATTTGCTTGTGGATCACTTTATGGAAC TTTACCATCAATCTGTGGTTTACCGGAAGCAAGCTGCCATGATCCTTAATGAACTGGTTA CAGGGGCTGCTGGGCTGGAGGTTGAGGATCTTCACGAAAAACATATTAAAACAAACCCAG AAGAACTGAGAGAGATTGTGACATCTATACTTGAAGAATACACAAGTCAAGAAAATTGGT ATTTGGTTACCTGTCTTGAAACTGAGGAAATGGGAGAGGAGCTGATGATGGAGCACCCAG GCCTCCAAGCCATCACGTCTGGTGAACACACCTGCCAAGTTACATCTTTTCTAGCCTTCT CAAAGCCAAGTCCCACTATTTGCTCCATGAACAGTAACATCTGGCAAATATGCATTCAGT TGGAAGGAATTGGCCAGTTTGCATATGCACTAGGAAAAGACTTCTGTTTGCTCTTGATGT CAGCCCTTTATCCAGTACTGGAGAAGGCTGGAGACCAAACCCTACTCATTAGTCAGGTGG CTACCAGCACCATGATGGACGTTTGCCGTGCTTGTGGCTACGACTCCCTGCAGCACCTGA TCAATCAAAATTCAGACTATTTAGTGAATGGGATCTCTTTAAATCTGCGTCATCTGGCTC TGCATCCTCATACCCCAAAGGTCCTGGAAGTCATGCTGCGGAACTCAGATGCTAACCTGC TTCCTTTGGTGGCAGATGTGGTTCAAGATGTCTTGGCCACCCTGGACCAATTTTACGATA AGAGAGCTGCTTCCTTTGTCAGCGTTCTGCATGCTCTGATGGCAGCATTAGCCCAGTGGT TCCCAGACACAGGTAATCTTGGGCACCTCCAAGAGCAAAGTTTAGGAGAAGAGGGAAGTC ATTTGAACCAAAGACCAGCAGCTCTTGAGAAGAGCACCACCACAGCTGAAGACATCGAAC AGTTTTTGCTGAACTACCTCAAAGAGAAGGATGTGGCAGATGGAAATGTCTCGGATTTTG ATAATGAAGAAGAGGAACAGTCAGTCCCTCCCAAAGTGGATGAGAATGACACCCGTCCAG ATGTGGAGCCACCACTGCCATTGCAGATCCAAATAGCCATGGACGTGATGGAACGCTGCA TCCACTTGTTGTCAGATAAAAATCTGCAAATCCGCCTGAAGGTCTTGGATGTGCTGGATC TGTGTGTGGTTGTTCTTCAGTCCCACAAAAACCAGCTGCTTCCCTTGGCTCATCAGGCCT GGCCCTCGCTCGTTCACCGACTCACACGGGACGCCCCCCTGGCAGTGCTTAGAGCCTTCA AGGTTTTACGTACCCTGGGAAGCAAGTGTGGTGACTTTCTTCGCAGCCGGTTCTGCAAAG ATGTCCTGCCAAAGCTGGCTGGCTCCCTAGTCACCCAGGCCCCCATCAGTGCCAGGGCTG GACCAGTTTACTCGCACACGCTGGCCTTCAAGTTGCAGCTGGCTGTCTTACAGGGCCTGG GCCCCCTCTGTGAGAGACTGGACCTAGGTGAGGGTGACCTGAATAAAGTGGCTGATGCCT GCTTGATTTACCTCAGTGTCAAACAGCCCGTGAAATTACAAGAGGCTGCCAGGAGCGTCT TCCTCCACTTGATGAAGGTGGACCCAGACTCCACCTGGTTCCTCCTGAACGAGCTTTACT GCCCCGTGCAGTTCACACCTCCCCACCCCAGCCTCCACCCTGTGCAGCTGCACGGGGCCA GCGGGCAGCAGAACCCCTACACGACCAACGTGCTCCAGCTGCTCAAGGAGCTGCAGTGAC CCTGCTCCCCCACCACAGAGGCCACCGATCCCTCCCCTACTGCCAGCCAGAAGCTGGGCT GACCCCACCCCGGCCATAGGCGGTGGCAGCGGCAGCAGAGAAGGTGAATTAGTTAGCCAA TCGATTTATAAATTGATCGATCACACAACTGCTTAGAAATGGATTGAAGGAAAGTAGCTG ACTATTATTTATATTTCATACCTTGTGTTTTCAAGTGACATTGTCTGGTGGCTCTAAGGG TTTAACCCCTTAGCCTACCATCTCTATAGCCCCAGCTCCCTCACAGGCCACACACACACA CACACAAGAGGTCAGTTCCCCTCCATCTGCATACACCTCCCTGTCTTCAAATAATGAGAT GGAACTAATTTGTTTTACCTAACCTGATCTTTGGGAAACAAACGGAAATAAAGACACTTC TTGGATGAAAAGTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_014657 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014657.1, NP_055472.1 |
| RefSeq Size | 3931 bp |
| RefSeq ORF | 3270 bp |
| Locus ID | 9675 |
| UniProt ID | O43156 |
| Gene Summary | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same isoform. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201622 | TTI1 (Myc-DDK-tagged)-Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1) |
CNY 7,584.00 |
|
| RC201622L1 | Lenti ORF clone of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), Myc-DDK-tagged |
CNY 9,984.00 |
|
| RC201622L2 | Lenti ORF clone of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), mGFP tagged |
CNY 11,210.00 |
|
| RC201622L3 | Lenti ORF clone of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), Myc-DDK-tagged |
CNY 11,210.00 |
|
| RC201622L4 | Lenti ORF clone of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), mGFP tagged |
CNY 11,210.00 |
|
| RG201622 | TTI1 (tGFP-tagged) - Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1) |
CNY 9,184.00 |
|
| SC100424 | TTI1 (untagged)-Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1) |
CNY 7,592.00 |
