BCKDHA (NM_000709) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC204816L1V
- LentiORF®
Lenti ORF particles, BCKDHA (Myc-DDK-tagged)-Human branched chain keto acid dehydrogenase E1, alpha polypeptide (BCKDHA), nuclear gene encoding mitochondrial protein, transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
Product Data | |
Product Name | BCKDHA (NM_000709) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | BCKDE1A; MSU; MSUD1; OVD1A |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_000709 |
ORF Size | 1335 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204816).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000709.3 |
RefSeq Size | 1791 bp |
RefSeq ORF | 1338 bp |
Locus ID | 593 |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Valine, leucine and isoleucine degradation |
MW | 50.9 kDa |
Gene Summary | The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
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