Fibromodulin (FMOD) (NM_002023) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC206534L1V
- LentiORF®
Lenti ORF particles, FMOD (Myc-DDK tagged) - Human fibromodulin (FMOD), 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
Product Data | |
Product Name | Fibromodulin (FMOD) (NM_002023) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | FM; SLRR2E |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_002023 |
ORF Size | 1128 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206534).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002023.3 |
RefSeq Size | 3271 bp |
RefSeq ORF | 1131 bp |
Locus ID | 2331 |
Domains | LRRNT, LRR, LRR_TYP, LRR_BAC, LRR_PS |
Protein Families | Druggable Genome, Secreted Protein |
MW | 43.2 kDa |
Gene Summary | Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
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