Eph receptor B6 (EPHB6) (NM_004445) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC229404L3V
- LentiORF®
Lenti ORF particles, EPHB6 (Myc-DDK-tagged)-Human EPH receptor B6 (EPHB6), 200ul, >10^7 TU/mL
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CNY 11,210.00
货期*
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规格
Cited in 1 publication. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | Eph receptor B6 (EPHB6) (NM_004445) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | HEP |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_004445 |
ORF Size | 3066 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC229404).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_004445.5 |
RefSeq Size | 3449 bp |
RefSeq ORF | 3069 bp |
Locus ID | 2051 |
Domains | pkinase, EPH_lbd, TyrKc, SAM, S_TKc, FN3 |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways | Axon guidance |
MW | 110.8 kDa |
Gene Summary | This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interaction.
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Cellular signalling
,PubMed ID 25152371
[EPHB6]
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