Human RhoGAP (ARHGAP5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP5
Locus ID	394
Kit Components	GA100284G1, RhoGAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100284G2, RhoGAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100284G3, RhoGAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001030055, NM_001173
Synonyms	GFI2; p190-B; p190BRhoGAP; RhoGAP5
Summary	Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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