Human GPR34 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GPR34
Locus ID	2857
Kit Components	GA101918G1, GPR34 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101918G2, GPR34 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101918G3, GPR34 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033513, NM_001033514, NM_001097579, NM_005300, N40174
Synonyms	G protein-coupled receptor 34; OTTHUMP00000023148; OTTHUMP00000023149
Summary	G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM, Apr 2006]

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