Human HLA-DQA2 activation kit by CRISPRa
CAT#: GA102128
HLA-DQA2 CRISPRa kit - CRISPR gene activation of human major histocompatibility complex, class II, DQ alpha 2
CNY 12,255.00
CNY 2,400.00
CNY 3,990.00
CNY 1,999.00
CNY 2,700.00
CNY 800.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | HLA-DQA2 |
Locus ID | 3118 |
Kit Components | GA102128G1, HLA-DQA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102128G2, HLA-DQA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102128G3, HLA-DQA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_020056 |
Synonyms | DX-ALPHA; HLA-DXA |
Summary | This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010] |
Documents
Resources
基因表达相关资源 |
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