Human OS9 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OS9
Locus ID	10956
Kit Components	GA107519G1, OS9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107519G2, OS9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107519G3, OS9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001017956, NM_001017957, NM_001017958, NM_001261420, NM_001261421, NM_001261422, NM_001261423, NM_006812
Synonyms	ERLEC2; OS-9
Summary	This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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