Human FLRT2 activation kit by CRISPRa

CAT#: GA108496

FLRT2 CRISPRa kit - CRISPR gene activation of human fibronectin leucine rich transmembrane protein 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
FLRT2 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


FLRT2 (Myc-DDK-tagged)-Human fibronectin leucine rich transmembrane protein 2 (FLRT2)
    • 10 ug

CNY 4,912.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol FLRT2
Locus ID 23768
Kit Components

GA108496G1, FLRT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108496G2, FLRT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108496G3, FLRT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001346143, NM_001346144, NM_001346145, NM_001346146, NM_013231, NR_144385, NR_144386, NR_144387
Summary This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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