Human UCH37 (UCHL5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UCHL5
Locus ID	51377
Kit Components	GA109775G1, UCH37 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109775G2, UCH37 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109775G3, UCH37 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199261, NM_001199262, NM_001199263, NM_015984, NR_037607, NM_001350840, NM_001350841, NM_001350842, NM_001350843, NM_001350844, NM_001350845, NM_001350846, NM_001350847, NM_001350848, NM_001350849, NM_001350850, NM_001350851, NM_001350852, NR_146930, NR_146931
Synonyms	CGI-70; INO80R; UCH-L5; UCH37
Summary	Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.[UniProtKB/Swiss-Prot Function]

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