Human C2ORF47 (MAIP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAIP1
Locus ID	79568
Kit Components	GA112459G1, C2ORF47 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112459G2, C2ORF47 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112459G3, C2ORF47 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_024520, NM_001369399, NR_161377
Synonyms	DKFZp666A212; FLJ22555
Summary	Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation (PubMed:27642048). Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB) (PubMed:27642048).[UniProtKB/Swiss-Prot Function]

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