Human Tumor necrosis factor alpha induced protein 8 like protein 2 (TNFAIP8L2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNFAIP8L2
Locus ID	79626
Kit Components	GA112498G1, Tumor necrosis factor alpha induced protein 8 like protein 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112498G2, Tumor necrosis factor alpha induced protein 8 like protein 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112498G3, Tumor necrosis factor alpha induced protein 8 like protein 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_024575
Synonyms	TIPE2
Summary	Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).[UniProtKB/Swiss-Prot Function]

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