Human VEPH1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	VEPH1
Locus ID	79674
Kit Components	GA112539G1, VEPH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112539G2, VEPH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112539G3, VEPH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001167911, NM_001167912, NM_001167915, NM_001167916, NM_001167917, NM_024621
Synonyms	MELT; VEPH
Summary	Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.[UniProtKB/Swiss-Prot Function]

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