Mouse Bmpr1a activation kit by CRISPRa
CAT#: GA200426
Bmpr1a CRISPRa kit - CRISPR gene activation of mouse bone morphogenetic protein receptor, type 1A
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Bmpr1a |
Locus ID | 12166 |
Kit Components | GA200426G1, Bmpr1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200426G2, Bmpr1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200426G3, Bmpr1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_009758 |
Synonyms | 1110037I22Rik; ALK3; AU045487; Bmpr; BMPR-IA |
Summary | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed:24098149). Mediates induction of adipogenesis by GDF6 (PubMed:23527555).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN502204 | Bmpr1a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |