Mouse Fkbp5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fkbp5
Locus ID	14229
Kit Components	GA201430G1, Fkbp5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201430G2, Fkbp5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201430G3, Fkbp5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010220
Synonyms	D17Ertd592e; Dit1; FKBP-5; FKBP51
Summary	Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.[UniProtKB/Swiss-Prot Function]

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