Mouse Eif6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Eif6
Locus ID	16418
Kit Components	GA202207G1, Eif6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202207G2, Eif6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202207G3, Eif6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010579
Synonyms	1110004P11; AA408895; CAB; eIF-6; imc-415; Itgb4bp; p27(BBP); p27BBP
Summary	The protein encoded by this gene is a eukaryotic translation initiation factor that regulates both ribosome biogenesis and translation, which are rate-limiting factors for cell growth. The encoded protein binds 60S ribosomes and prevents their association with 40S ribosomes. This gene may play a role in oncogenesis as well. [provided by RefSeq, Aug 2015]

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