Mouse Ptprz1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptprz1
Locus ID	19283
Kit Components	GA203502G1, Ptprz1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203502G2, Ptprz1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203502G3, Ptprz1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081306, NM_001311064, NM_001361349, NM_011219, NM_178180
Synonyms	AI850339; DSD-1-PG; PTPbeta; Ptprz; Ptpz; PTPzeta; R-PTP-zeta; Rptpbeta; RPTPz
Summary	Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades.[UniProtKB/Swiss-Prot Function]

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