Mouse Rasa4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rasa4
Locus ID	54153
Kit Components	GA205650G1, Rasa4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205650G2, Rasa4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205650G3, Rasa4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001039103, NM_133914
Synonyms	AA793972; AW112107; BB079060; CAPRI; GAPL
Summary	Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. Isoform 2 activates the Ras pathway and promotes RANKL shedding by modulating the expression of MMP14.[UniProtKB/Swiss-Prot Function]

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