Mouse Sh2d4a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sh2d4a
Locus ID	72281
Kit Components	GA209180G1, Sh2d4a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209180G2, Sh2d4a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209180G3, Sh2d4a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_028182
Synonyms	2210402M20Rik; SH2A
Summary	Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation (By similarity). May play a role in T-cell development and function.[UniProtKB/Swiss-Prot Function]

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