Mouse Jmjd1c activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Jmjd1c
Locus ID	108829
Kit Components	GA212148G1, Jmjd1c gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212148G2, Jmjd1c gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212148G3, Jmjd1c gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001242396, NM_207221
Synonyms	5430433L24Rik; D630035I23Rik; Jmjdic; TRIP8
Summary	Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).[UniProtKB/Swiss-Prot Function]

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