CD71 (TFRC) Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA	RFP-BSD
Symbol	CD71
Locus ID	7037
Kit Components	KN200980G1, CD71 gRNA vector 1 in pCas-Guide CRISPR vector KN200980G2, CD71 gRNA vector 2 in pCas-Guide CRISPR vector KN200980RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001128148, NM_001313965, NM_001313966, NM_003234
Synonyms	CD71; IMD46; p90; T9; TFR; TFR1; TR; TRFR
Summary	This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

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