Nesprin 1 (SYNE1) Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	Nesprin 1
Locus ID	23345
Kit Components	KN212694G1, Nesprin 1 gRNA vector 1 in pCas-Guide CRISPR vector KN212694G2, Nesprin 1 gRNA vector 2 in pCas-Guide CRISPR vector KN212694BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_015293, NM_033071, NM_133650, NM_182961, NM_001347701, NM_001347702
Synonyms	8B; ARCA1; C6orf98; CPG2; dJ45H2.2; DKFZp781J13156; EDMD4; FLJ30878; FLJ41140; KIAA0796
Summary	This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.