Scrambled shRNA control in pGFP-C-shLenti shRNA Vector

CAT＃: TR30021

29-mer Scrambled shRNA Cassette in pGFP-C-shLenti Vector, 5 ug

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CNY 2,000.00

货期*
4周
规格
    • 5 ug
Cited in 159 publications.

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Product Data
Product Name Scrambled shRNA control in pGFP-C-shLenti shRNA Vector
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (159)

The use of this RNAi has been cited in the following citations:
THOC2 expression and its impact on 5-fluorouracil resistance in glioblastoma multiforme ,null, American Journal of Cancer Research ,PubMed ID 37424800
A disintegrin and metalloprotease 12 contributes to colorectal cancer metastasis by regulating epithelial-mesenchymal transition ,null, International Journal of Oncology ,PubMed ID 36866761
An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma ,null, Nature Communications ,PubMed ID 37015919
Targeting the secreted RGDKGE collagen fragment reduces PD‑L1 by a proteasome‑dependent mechanism and inhibits tumor growth. ,null, Oncology reports ,PubMed ID 36633146
Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin ,null, International Journal of Oncology ,PubMed ID 36382671
A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration ,null, Developmental cell ,PubMed ID 36626870
Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy. ,null, Journal of advanced research ,PubMed ID 36334887
Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia ,null, JCI Insight ,PubMed ID 36345943
Complementary anti-cancer pathways triggered by inhibition of sideroflexin 4 in ovarian cancer ,null, Scientific Reports ,PubMed ID 36402786
Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity ,null, Journal for Immunotherapy of Cancer ,PubMed ID 36427906
The TLK1–MK5 Axis Regulates Motility, Invasion, and Metastasis of Prostate Cancer Cells ,null, Cancers ,PubMed ID 36497211
The STIM1/2-Regulated Calcium Homeostasis Is Impaired in Hippocampal Neurons of the 5xFAD Mouse Model of Alzheimer’s Disease ,null, International Journal of Molecular Sciences ,PubMed ID 36499137
DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting ,null, Cell reports ,PubMed ID 36044864
The role of FYCO1-dependent autophagy in lens fiber cell differentiation. ,null, Autophagy ,PubMed ID 35343376
Cadherin‐3 is a novel oncogenic biomarker with prognostic value in glioblastoma ,null, Molecular Oncology ,PubMed ID 34919784
The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus ,null, eLife ,PubMed ID 35467530
The roles of HMGB1‐produced DNA gaps in DNA protection and aging biomarker reversal, et al. The roles of HMGB1‐produced DNA gaps in DNA protection and aging biomarker reversal ,null, FASEB BioAdvances ,PubMed ID 35664831
Matrix Metalloproteinase-1 (MMP1) Upregulation through Promoter Hypomethylation Enhances Tamoxifen Resistance in Breast Cancer ,null, Cancers ,PubMed ID 35267540
Targeting prooxidant MnSOD effect inhibits triple-negative breast cancer (TNBC) progression and M2 macrophage functions under the oncogenic stress ,null, Cell Death & Disease ,PubMed ID 35017469
Wnt5A and TGFβ1 Converges through YAP1 Activity and Integrin Alpha v Up-Regulation Promoting Epithelial to Mesenchymal Transition in Ovarian Cancer Cells and Mesothelial Cell Activation ,null, Cells ,PubMed ID 35053353
MED10 Drives the Oncogenicity and Refractory Phenotype of Bladder Urothelial Carcinoma Through the Upregulation of hsa-miR-590 ,null, Frontiers in Oncology ,PubMed ID 35096564
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3 ,null, Cell Death & Disease ,PubMed ID 34876563
PER2 mediates CREB-dependent light induction of the clock gene Per1 ,null, Scientific Reports ,PubMed ID 34741086
Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells ,null, International Journal of Molecular Sciences ,PubMed ID 34830078
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer’s disease ,null, Acta Neuropathologica Communications ,PubMed ID 34663454
DUOX2, a New Biomarker for Disseminated Gastric Cancer’s Response to Low Dose Radiation in Mice ,null, Cancers ,PubMed ID 34439340
SKAP2 as a new regulator of oligodendroglial migration and myelin sheath formation ,null, Glia ,PubMed ID 34324225
Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup ,null, Life Science Alliance ,PubMed ID 34183444
Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer ,Coll-SanMartin, L;Davalos, V;Pi?eyro, D;Rossell?-Tortella, M;Bueno-Costa, A;Setien, F;Villanueva, A;Granada, I;Ruiz-Xiviller, N;Kotter, A;Helm, M;Yokota, J;Kawabata-Iwakawa, R;Kohno, T;Esteller, M;, Cancers ,PubMed ID 33919717 [Scrambled Control]
Pharmacological Inhibition of Insulin Growth Factor-1 Receptor (IGF-1R) Alone or in Combination With Ruxolitinib Shows Therapeutic Efficacy in Preclinical Myeloproliferative Neoplasm Models ,null, HemaSphere ,PubMed ID 33954282
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism ,Ueda, K;Kumari, R;Schwenger, E;Wheat, JC;Bohorquez, O;Narayanagari, SR;Taylor, SJ;Carvajal, LA;Pradhan, K;Bartholdy, B;Todorova, TI;Goto, H;Sun, D;Chen, J;Shan, J;Song, Y;Montagna, C;Xiong, S;Lozano, G;Pellagatti, A;Boultwood, J;Verma, A;Steidl, U;, Cancer cell ,PubMed ID 33667384 [Scrambled Control]
Attenuation of MAMLD1 Expression Suppresses the Growth and Migratory Properties of Gonadotroph Pituitary Adenomas. ,null, Pathology oncology research : POR ,PubMed ID 30911995
Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL) ,Shaw, TI;Dong, L;Tian, L;Qian, C;Liu, Y;Ju, B;High, A;Kavdia, K;Pagala, VR;Shaner, B;Pei, D;Easton, J;Janke, LJ;Porter, SN;Ma, X;Cheng, C;Pruett-Miller, SM;Choi, J;Yu, J;Peng, J;Gu, W;Look, AT;Downing, JR;Zhang, J;, Scientific reports ,PubMed ID 33664368 [Scrambled Control]
Prodromal Alzheimer\'s Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer\'s Pathology ,de Vidania, S;Palomares-Perez, I;Frank-García, A;Saito, T;Saido, TC;Draffin, J;Szaruga, M;Chávez-Gutierrez, L;Calero, M;Medina, M;Guix, FX;Dotti, CG;, Frontiers in neuroscience ,PubMed ID 33343276 [Scrambled Control]
The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo ,null, The Journal of Physiology ,PubMed ID 33258480
Pharmacogenomics of intracellular methotrexate polyglutamates in patients’ leukemia cells in vivo ,null, The Journal of Clinical Investigation ,PubMed ID 33164984
Nidogen 1 regulates proliferation and migration/invasion in murine claudin-low mammary tumor cells ,null, Oncology Letters ,PubMed ID 33281963
Molecular Motor KIF3B Acts as a Key Regulator of Dendritic Architecture in Cortical Neurons ,null, Frontiers in Cellular Neuroscience ,PubMed ID 33192305
Matrin-3 plays an important role in cell cycle and apoptosis for survival in malignant melanoma ,Kuriyama, H;Fukushima, S;Kimura, T;Okada, E;Ishibashi, T;Mizuhashi, S;Kanemaru, H;Kajihara, I;Makino, K;Miyashita, A;Aoi, J;Okada, S;Ihn, H;Kita, K;, J. Dermatol. Sci. ,PubMed ID 32943284 [Scrambled Control]
GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma ,Hayashi, M;Guida, E;Inokawa, Y;Goldberg, R;Reis, LO;Ooki, A;Pilli, M;Sadhukhan, P;Woo, J;Choi, W;Izumchenko, E;Gonzalez, LM;Marchionni, L;Zhavoronkov, A;Brait, M;Bivalacqua, T;Baras, A;Netto, GJ;Koch, W;Singh, A;Hoque, MO;, Sci Signal ,PubMed ID 32817372 [Scrambled Control]
Autophagy regulates trophoblast invasion by targeting NF-κB activity ,null, Scientific Reports ,PubMed ID 32820194
Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells ,null, Nature Communications ,PubMed ID 32620744
LIX1 regulates YAP activity and controls gastrointestinal cancer cell plasticity, et al. LIX1 regulates YAP activity and controls gastrointestinal cancer cell plasticity ,null, Journal of Cellular and Molecular Medicine ,PubMed ID 32633461
Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development ,null, The Journal of Neuroscience ,PubMed ID 32414783
PKM2 inhibition may reverse therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma ,null, Journal of Experimental & Clinical Cancer Research : CR ,PubMed ID 32487192
Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling ,Xie, H;Heier, C;Kien, B;Vesely, PW;Tang, Z;Sexl, V;Schoiswohl, G;Strießnig-Bina, I;Hoefler, G;Zechner, R;Schweiger, M;, Biochim Biophys Acta Mol Cell Biol Lipids ,PubMed ID 32404277 [Negative Control]
ETS1 Suppresses Tumorigenesis of Human Breast Cancer via Trans-Activation of Canonical Tumor Suppressor Genes ,Kim, GC;Lee, CG;Verma, R;Rudra, D;Kim, T;Kang, K;Nam, JH;Kim, Y;Im, SH;Kwon, HK;, Front Oncol ,PubMed ID 32477936 [Negative Control]
Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema ,Kitchen, P;Salman, MM;Halsey, AM;Clarke-Bland, C;MacDonald, JA;Ishida, H;Vogel, HJ;Almutiri, S;Logan, A;Kreida, S;Al-Jubair, T;Winkel Missel, J;Gourdon, P;Törnroth-Horsefield, S;Conner, MT;Ahmed, Z;Conner, AC;Bill, RM;, Cell ,PubMed ID 32413299 [Negative Control]
Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling via PHLPP1 in colorectal cancer ,null, Cancer Biology & Medicine ,PubMed ID 32587773
Pbrm1 Steers Mesenchymal Stromal Cell Osteolineage Differentiation by Integrating PBAF-Dependent Chromatin Remodeling and BMP/TGF-β Signaling ,Sinha, S;Biswas, M;Chatterjee, SS;Kumar, S;Sengupta, A;, Cell Rep ,PubMed ID 32348751 [Negative Control]
PAUF/ZG16B promotes colorectal cancer progression through alterations of the mitotic functions and the Wnt/β-catenin pathway. ,null, Carcinogenesis ,PubMed ID 31095674
Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT ,El-Sehemy, A;Selvadurai, HJ;Ortin-Martinez, A;Pokrajac, NT;Mamatjan, Y;Tachibana, N;Rowland, KJ;Lee, L;Park, NI;Aldape, KD;Dirks, P;Wallace, VA;, J. Clin. Invest. ,PubMed ID 32182224 [Scrambled Control]
Alpha-Catulin, a New Player in a Rho Dependent Apical Constriction That Contributes to the Mouse Neural Tube Closure ,Karpińska, K;Cao, C;Yamamoto, V;Gielata, M;Kobielak, A;, Front. Cell Dev. Biol. ,PubMed ID 32258033 [Negative Control]
Heat Shock Protein 47 Maintains Cancer Cell Growth by Inhibiting the Unfolded Protein Response Transducer IRE1α ,Yoneda, A;Sakai-Sawada, K;Minomi, K;Tamura, Y;, Mol. Cancer Res. ,PubMed ID 32102897 [Scrambled Control]
Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior ,Salesse, C;Charest, J;Doucet-Beaupré, H;Castonguay, AM;Labrecque, S;De Koninck, P;Lévesque, M;, Cell Rep ,PubMed ID 32075770 [Negative Control]
Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis ,De Fusco, A;Cerullo, MS;Marte, A;Michetti, C;Romei, A;Castroflorio, E;Baulac, S;Benfenati, F;, Neurobiol. Dis. ,PubMed ID 32113911 [Negative Control]
The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I ,Bufalieri, F;Caimano, M;Lospinoso Severini, L;Basili, I;Paglia, F;Sampirisi, L;Loricchio, E;Petroni, M;Canettieri, G;Santoro, A;D'Angelo, L;Infante, P;Di Marcotullio, L;, Cancers (Basel) 2020 ,PubMed ID 32019099 [Negative Control]
Interference with SMO increases chemotherapy drug sensitivity of A2780/DDP cells by inhibiting the Hh/Gli signaling pathway ,Ma, S;Liu, D;Tan, W;Du, B;Liu, W;Li, W;Jiao, Y;, J. Cell. Biochem. ,PubMed ID 31904145 [Negative Control]
STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons ,null, Cells ,PubMed ID 31936514
AGO2 mediates MYC mRNA stability in hepatocellular carcinoma ,null, Molecular cancer research : MCR ,PubMed ID 31941754
Long Noncoding RNA (lncRNA) Maternally Expressed Gene 3 (MEG3) Participates in Chronic Obstructive Pulmonary Disease through Regulating Human Pulmonary Microvascular Endothelial Cell Apoptosis ,Bi, H;Wang, G;Li, Z;Zhou, L;Zhang, M;Ye, J;Wang, Z;, Med Sci Monit ,PubMed ID 32201430 [Negative Control]
miR-181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart ,Banavath, HN;Roman, B;Mackowski, N;Biswas, D;Afzal, J;Nomura, Y;Solhjoo, S;O'Rourke, B;Kohr, M;Murphy, E;Steenbergen, C;Das, S;, J Am Heart Assoc ,PubMed ID 31801413 [Negative Control]
The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells ,null, Cancer Cell International ,PubMed ID 31827395
Persistent double strand break accumulation does not precede cell death in an Olaparib-sensitive BRCA-deficient colorectal cancer cell model ,null, Genetics and Molecular Biology ,PubMed ID 31930278
The future of plant biotechnology in a globalized and environmentally endangered world ,Montagu, M;, Genet. Mol. Biol. ,PubMed ID 31930275 [Negative Control]
Mechanism associated with aberrant lncRNA MEG3 expression in gestational diabetes mellitus ,Zhang, H;, Exp Ther Med ,PubMed ID 31656536 [Negative Control]
Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock ,null, eLife ,PubMed ID 31687929
Nitrate uptake and metabolism in human skeletal muscle cell cultures ,Srihirun, S;Park, JW;Teng, R;Sawaengdee, W;Piknova, B;Schechter, AN;, Nitric Oxide ,PubMed ID 31604144 [Negative Control]
Targeting the kynurenine pathway for the treatment of cisplatin resistant lung cancer ,null, Molecular cancer research : MCR ,PubMed ID 31628200
Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons. ,null, Journal of cell science ,PubMed ID 31427429
NPC1 enables cholesterol mobilization during long‐term potentiation that can be restored in Niemann–Pick disease type C by CYP46A1 activation ,null, EMBO Reports ,PubMed ID 31535451
EK7 Regulates NLRP3 Inflammasome Activation and Neuroinflammation Post-traumatic Brain Injury ,Chen, Y;Meng, J;Bi, F;Li, H;Chang, C;Ji, C;Liu, W;, Front Mol Neurosci ,PubMed ID 31555089 [Negative Control]
Prolactin promotes fibrosis and pancreatic cancer progression ,Tandon, M;Coudriet, GM;Criscimanna, A;Socorro, M;Eliliwi, M;Singhi, AD;Cruz-Monserrate, Z;Bailey, P;Lotze, MT;Zeh, H;Hu, J;Goffin, V;Gittes, GK;Biankin, AV;Esni, F;, Cancer Res. ,PubMed ID 31395607 [Negative Control]
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer disease risk ,null, Science translational medicine ,PubMed ID 31413141
Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cells ,Li, H;Lim, HC;Zacharaki, D;Xian, X;Kenswil, KJ;Bräunig, S;Raaijmakers, MH;Woods, NB;Hansson, J;Scheding, S;, Haematologica ,PubMed ID 31371413 [Negative Control]
Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo ,null, Mediators of Inflammation ,PubMed ID 31396016
HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding ,Gruber, J;Geller, B;Lipchik, A;Chen, J;Salahudeen, A;Ram, A;Ford, J;Kuo, C;Snyder, M;, Molecular Cell ,PubMed ID 31278053 [Negative Control]
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations. ,null, Molecular cell ,PubMed ID 31202576
SORLA regulates endosomal trafficking and oncogenic fitness of HER2 ,Pietilä, M;Sahgal, P;Peuhu, E;Jäntti, NZ;Paatero, I;Närvä, E;Al-Akhrass, H;Lilja, J;Georgiadou, M;Andersen, OM;Padzik, A;Sihto, H;Joensuu, H;Blomqvist, M;Saarinen, I;Boström, PJ;Taimen, P;Ivaska, J;, Nat Commun ,PubMed ID 31138794 [Negative Control]
TNF-α/IL-1β-licensed mesenchymal stromal cells promote corneal allograft survival via myeloid cell-mediated induction of Foxp3+ regulatory T cells in the lung. ,null, FASEB journal : official publication of the Federation of American Societies for Experimental Biology ,PubMed ID 31108041
Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF ,null, EBioMedicine ,PubMed ID 31129098
Reduced Basal Nitric Oxide Production Induces Precancerous Mammary Lesions via ERBB2 and TGFβ ,Ren, G;Zheng, X;Bommarito, M;Metzger, S;Walia, Y;Letson, J;Schroering, A;Kalinoski, A;Weaver, D;Figy, C;Yeung, K;Furuta, S;, Sci Rep ,PubMed ID 31040372 [Negative Control]
miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma ,Zhang, W;Wells, J;Chow, K;Huang, H;Yuan, M;Saxena, T;Melnick, M;Politi, K;Asara, J;Costa, D;Bult, C;Slack, F;, Nat Metab [Negative Control]
YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells ,null, Nature Communications ,PubMed ID 30931946
Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness ,null, Oncogene ,PubMed ID 30967630
Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells. ,null, Leukemia ,PubMed ID 30988378
miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma ,null, Nature metabolism ,PubMed ID 31535082
Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2 ,Zhu, B;Cao, A;Li, J;Young, J;Wong, J;Ashraf, S;Bierzynska, A;Menon, M;Hou, S;Sawyers, C;Campbell, K;Saleem, M;He, J;Hildebrandt, F;D’Agati, V;Peng, W;Kaufman, L;, Kidney International [Negative Control]
Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2 ,null, Kidney international ,PubMed ID 31171376
Loss of RNA-binding protein GRSF1 activates mTOR to elicit a proinflammatory transcriptional program ,Noh, JH;Kim, KM;Pandey, PR;Noren Hooten, N;Munk, R;Kundu, G;De, S;Martindale, JL;Yang, X;Evans, MK;Abdelmohsen, K;Gorospe, M;, Nucleic Acids Res. ,PubMed ID 30753671 [Negative Control]
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment ,Li, L;Wang, Y;Torkelson, JL;Shankar, G;Pattison, JM;Zhen, HH;Fang, F;Duren, Z;Xin, J;Gaddam, S;Melo, SP;Piekos, SN;Li, J;Liaw, EJ;Chen, L;Li, R;Wernig, M;Wong, WH;Chang, HY;Oro, AE;, Cell Stem Cell ,PubMed ID 30686763 [Negative Control]
MBD3/NuRD loss participates with KDM6A program to promote DOCK5/8 expression and Rac GTPase activation in human acute myeloid leukemia. ,null, FASEB journal : official publication of the Federation of American Societies for Experimental Biology ,PubMed ID 30668141
DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways ,Katase, N;Nishimatsu, SI;Yamauchi, A;Yamamura, M;Fujita, S;, Int. J. Oncol. ,PubMed ID 30569110 [Negative Control]
Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma ,Nickel, AC;Wan, XY;Saban, DV;Weng, YL;Zhang, S;Keyvani, K;Sure, U;Zhu, Y;, J. Neurooncol. ,PubMed ID 30392087 [Negative Control]
Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain ,null, Developmental Neuroscience ,PubMed ID 30399610
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 ,Hulse, M;Caruso, LB;Madzo, J;Tan, Y;Johnson, S;Tempera, I;, PLoS Pathog. ,PubMed ID 30395643 [Negative Control]
Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1 ,Singhal, A;Szente, L;Hildreth, JEK;Song, B;, Cell Death Dis ,PubMed ID 30282967 [Negative Control]
Modelling ponatinib resistance in tyrosine kinase inhibitor-naïve and dasatinib resistant BCR-ABL1+ cell lines ,null, Oncotarget ,PubMed ID 30410673
Huntingtin-Associated Protein 1A Regulates Store-Operated Calcium Entry in Medium Spiny Neurons From Transgenic YAC128 Mice, a Model of Huntington’s Disease ,Czeredys, M;Vigont, V;Boeva, V;Mikoshiba, K;Kaznacheyeva, E;Kuznicki, J;, Front. Cell. Neurosci. ,PubMed ID 30455632 [Scrambled Control]
Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer ,Coscia, F;Lengyel, E;Duraiswamy, J;Ashcroft, B;Bassani-Sternberg, M;Wierer, M;Johnson, A;Wroblewski, K;Montag, A;Yamada, SD;López-Méndez, B;Nilsson, J;Mund, A;Mann, M;Curtis, M;, Cell ,PubMed ID 30241606 [Negative Control]
Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis. ,null, Journal of pineal research ,PubMed ID 30091203
A facile in vitro platform to study cancer cell dormancy under hypoxic microenvironments using CoCl2 ,null, Journal of Biological Engineering ,PubMed ID 30127847
Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma. ,null, Biology of the cell ,PubMed ID 29907957
Epigenetically regulated PAX6 drives cancer cells toward a stem-like state via GLI-SOX2 signaling axis in lung adenocarcinoma ,Ooki, A;Dinalankara, W;Marchionni, L;Tsay, JJ;Goparaju, C;Maleki, Z;Rom, WN;Pass, HI;Hoque, MO;, Oncogene ,PubMed ID 29980786 [Negative Control]
The matrix protein Fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion ,null, Oncotarget ,PubMed ID 30046386
LncRNA ZEB2-AS1 promotes pancreatic cancer cell growth and invasion through regulating the miR-204/HMGB1 axis ,Gao, H;Gong, N;Ma, Z;Miao, X;Chen, J;Cao, Y;Zhang, G;, Int. J. Biol. Macromol. ,PubMed ID 29753015 [pGFP-C-shLenti]
p16 Controls p53 Protein Expression Through miR-dependent Destabilization of MDM2. ,null, Molecular cancer research : MCR ,PubMed ID 29739873
Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells ,Kim, JY;Lee, JS;Hwang, HS;Lee, DR;Park, CY;Jung, SJ;You, YR;Kim, DS;Kim, DW;, Exp. Mol. Med. ,PubMed ID 29650976 [pGFP-C-shLenti]
Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target. ,null, Science translational medicine ,PubMed ID 29669855
SORLA-driven endosomal trafficking regulates the oncogenic fitness of HER2 ,Pietila, M;Sahgal, P;Peuhu, E;Jantti, N;Paatero, I;Andersen, O;Padzik, A;Blomqvist, M;Saarinen, I;Bostrom, P;Taimen, P;Ivaska, J;, bioRxiv [Negative Control]
Knockdown of ZEB1 suppressed the formation of vasculogenic mimicry and epithelial-mesenchymal transition in the human breast cancer cell line MDA-MB-231 ,Liang, W;Song, S;Xu, Y;Li, H;Liu, H;, Mol Med Rep ,PubMed ID 29512767 [Negative Control]
Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death ,null, Scientific Reports ,PubMed ID 29559661
Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation. ,null, Science (New York, N.Y.) ,PubMed ID 29146868
Reduced N-Type Ca2+Channels in Atrioventricular Ganglion Neurons Are Involved in Ventricular Arrhythmogenesis ,Zhang, D;Tu, H;Cao, L;Zheng, H;Muelleman, RL;Wadman, MC;Li, YL;, J Am Heart Assoc ,PubMed ID 29335317 [Negative Control]
Sphingosine 1-phosphate regulates proliferation, cell cycle and apoptosis of hepatocellular carcinoma cells via syndecan-1 ,Zeng, Y;Liu, X;Yan, Z;Xie, L;, Prog. Biophys. Mol. Biol.2017 ,PubMed ID 29180036 [Negative Control]
The role and clinical significance of the CXCL17-CXCR8 (GPR35) axis in breast cancer. ,null, Biochemical and biophysical research communications ,PubMed ID 28943434
Gpr158 mediates osteocalcin’s regulation of cognition ,null, The Journal of Experimental Medicine ,PubMed ID 28851741
Innate sensing of influenza A virus hemagglutinin glycoproteins by the host endoplasmic reticulum (ER) stress pathway triggers a potent antiviral response via ER-associated protein degradation ,Frabutt, DA;Wang, B;Riaz, S;Schwartz, RC;Zheng, YH;, J. Virol. ,PubMed ID 29046440 [Negative Control]
Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons ,Jackson, TC;Kotermanski, SE;Kochanek, PM;, Neuroscience ,PubMed ID 28818525 [pGFP-C-shLenti]
Proinflammatory CXCL12-CXCR4/CXCR7 signaling axis drives Myc-induced prostate cancer in obese mice ,null, Cancer research ,PubMed ID 28687617
EGFL7 participates in regulating biological behavior of growth hormone-secreting pituitary adenomas via Notch2/DLL3 signaling pathway. ,null, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine ,PubMed ID 28705113
DEK protein level is a biomarker of CD138positive normal and malignant plasma cells ,null, PLoS ONE ,PubMed ID 28558048
Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA ,null, Genes & Development ,PubMed ID 28637693
A novel AHI-1–BCR-ABL–DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy ,null, Leukemia ,PubMed ID 28366933
Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination ,Zan, H;Tat, C;Qiu, Z;Taylor, JR;Guerrero, JA;Shen, T;Casali, P;, Nat Commun ,PubMed ID 28176781 [Negative Control]
Astrocyte-induced Reelin expression drives proliferation of Her2+ breast cancer metastases ,null, Clinical & experimental metastasis ,PubMed ID 28210910
Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration ,Brügger, V;Duman, M;Bochud, M;Münger, E;Heller, M;Ruff, S;Jacob, C;, Nat Commun ,PubMed ID 28139683 [Negative Control]
CFTR impairment upregulates c-Src activity through IL-1β autocrine signaling. ,null, Archives of biochemistry and biophysics ,PubMed ID 28088327
ICAM-5/Telencephalin Is a Functional Entry Receptor for Enterovirus D68. ,null, Cell host microbe ,PubMed ID 27923705
Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease ,Pérez-Cañamás, A;Benvegnù, S;Rueda, CB;Rábano, A;Satrústegui, J;Ledesma, MD;, Mol. Psychiatry ,PubMed ID 27620840
Platelet integrin a6ß1 controls lung metastasis through direct binding to cancer cell-derived ADAM9 ,Mammadova-Bach, E;Zigrino, P;Brucker, C;Bourdon, C;Freund, M;De Arcangelis, A;Abrams, SI;Orend, G;Gachet, C;Mangin, PH;, JCI Insight ,PubMed ID 27699237
Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-ß autocrine loop ,Zeng, Y;Yao, X;Chen, L;Yan, Z;Liu, J;Zhang, Y;Feng, T;Wu, J;Liu, X;, Oncotarget ,PubMed ID 27556509
Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway. ,null, Stem cells (Dayton, Ohio) ,PubMed ID 27502039
MNX1 is oncogenically upregulated in African-American prostate cancer ,null, Cancer research ,PubMed ID 27578002
Epstein-Barr Virus Oncoprotein LMP1 Mediates Epigenetic Changes in Host Gene Expression through PARP1 ,Martin, KA;Lupey, LN;Tempera, I;, J. Virol. ,PubMed ID 27440880
Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells ,Dolma, S;Selvadurai, HJ;Lan, X;Lee, L;Kushida, M;Voisin, V;Whetstone, H;So, M;Aviv, T;Park, N;Zhu, X;Xu, C;Head, R;Rowland, KJ;Bernstein, M;Clarke, ID;Bader, G;Harrington, L;Brumell, JH;Tyers, M;Dirks, PB;, Cancer Cell ,PubMed ID 27300435
Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors ,null, Oncotarget ,PubMed ID 27153561
Characterization of SKAP/Kinastrin isoforms - The N-terminus defines tissue specificity and Pontin binding ,Vranesic, AC;Reiche, J;Hoischen, C;Wohlmann, A;Bratsch, J;Friedrich, K;Günes, B;Cappallo-Obermann, H;Kirchhoff, C;Diekmann, S;Günes, C;Huber, O;, Hum. Mol. Genet. ,PubMed ID 27170314
β-Cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. ,null, American journal of physiology. Endocrinology and metabolism ,PubMed ID 27221116
OCT-4: a novel estrogen receptor-a collaborator that promotes tamoxifen resistance in breast cancer cells ,Bhatt, S;Stender, JD;Joshi, S;Wu, G;Katzenellenbogen, BS;, Oncogene ,PubMed ID 27065334
FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1 ,Khan, SY;Vasanth, S;Kabir, F;Gottsch, JD;, Nature Communications ,PubMed ID 27218149
Heterogenous ribonucleoprotein A18 (hnRNP A18) promotes tumor growth by increasing protein translation of selected transcripts in cancer cells ,null, Oncotarget ,PubMed ID 26824423
NF-YA splice variants have different roles on muscle differentiation ,Basile, V;Baruffaldi, F;Dolfini, D;Belluti, S;Benatti, P;Ricci, L;Artusi, V;Tagliafico, E;Mantovani, R;Molinari, S;Imbriano, C;, Biochim. Biophys. Acta ,PubMed ID 26921500
Disruption of nuclear factor (erythroid-derived-2)–like 2 antioxidant signaling: a mechanism for impaired activation of stem cells and delayed regeneration of skeletal muscle ,null, The FASEB Journal ,PubMed ID 26839378
Crizotinib Synergizes with Chemotherapy in Preclinical Models of Neuroblastoma ,null, Clinical cancer research : an official journal of the American Association for Cancer Research ,PubMed ID 26438783
Cell type-dependent modulation of the gene encoding heat shock protein HSPA2 by hypoxia-inducible factor HIF-1: Down-regulation in keratinocytes and up-regulation in HeLa cells. ,null, Biochimica et biophysica acta ,PubMed ID 26164067
Targeting the MLL complex in castration-resistant prostate cancer ,Malik, R;Khan, AP;Asangani, IA;Cieslik, M;Prensner, JR;Wang, X;Iyer, MK;Jiang, X;Borkin, D;Escara-Wilke, J;Stender, R;Wu, YM;Niknafs, YS;Jing, X;Qiao, Y;Palanisamy, N;Kunju, LP;Krishnamurthy, PM;Yocum, AK;Mellacheruvu, D;Nesvizhskii, AI;Cao, X;Dhanasekaran, SM;Feng, FY;Grembecka, J;Cierpicki, T;Chinnaiyan, AM;, Nat. Med. ,PubMed ID 25822367 [TR30021]
α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation ,null, Proceedings of the National Academy of Sciences of the United States of America ,PubMed ID 25825709
Proteolytic Activation of the Protease-activated Receptor (PAR)-2 by the Glycosylphosphatidylinositol-anchored Serine Protease Testisin * ,null, The Journal of Biological Chemistry ,PubMed ID 25519908
Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines ,null, Stem Cell Research & Therapy ,PubMed ID 25559585
MED1 mediates androgen receptor splice variant induced gene expression in the absence of ligand ,null, Oncotarget ,PubMed ID 25481872
Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget ,null, Oncotarget ,PubMed ID 25669982
Rapid neurogenesis through transcriptional activation in human stem cells ,null, Molecular Systems Biology ,PubMed ID 25403753
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells ,Flach, J;Bakker, ST;Mohrin, M;Conroy, PC;Pietras, EM;Reynaud, D;Alvarez, S;Diolaiti, ME;Ugarte, F;Forsberg, EC;Le Beau, MM;Stohr, BA;Méndez, J;Morrison, CG;Passegué, E;, Nature July 2014 ,PubMed ID 25079315 [PCMVMIR]
A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect ,null, Nature Communications ,PubMed ID 24699711
Chymase Mediates Injury and Mitochondrial Damage in Cardiomyocytes during Acute Ischemia/Reperfusion in the Dog ,null, PLoS ONE ,PubMed ID 24733352
Mx2 is an interferon induced inhibitor of HIV-1 infection ,null, Nature ,PubMed ID 24121441
The Mitochondrial Complex I Activity Is Reduced in Cells with Impaired Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function ,null, PLoS ONE ,PubMed ID 23185247
Interconnected contribution of tissue morphogenesis and the nuclear protein NuMA to the DNA damage response ,null, Journal of Cell Science ,PubMed ID 22331358
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