MAD3 (MXD3) (NM_031300) Human Mass Spec Standard

Specifications

Product Data
Description	MXD3 MS Standard C13 and N15-labeled recombinant protein (NP_112590)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200747
Predicted MW	23.5 kDa
Protein Sequence	Sequence Link (showhide) >RC200747 protein sequence Red=Cloning site Green=Tags(s) MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRR AQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGL AGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFVAGQEHSYSHGGGAWL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_112590
RefSeq Size	1483
RefSeq ORF	618
Synonyms	BHLHC13; MAD3; MYX
Locus ID	83463
Cytogenetics	5q35.3
Summary	This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]
Protein Families	Druggable Genome, Transcription Factors

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