cvHSP (HSPB7) (NM_014424) Human Mass Spec Standard

Specifications

Product Data
Description	HSPB7 MS Standard C13 and N15-labeled recombinant protein (NP_055239)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202861
Predicted MW	18.6 kDa
Protein Sequence	Sequence Link (showhide) >RC202861 protein sequence Red=Cloning site Green=Tags(s) MSHRTSSTFRAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPARPG GAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSA LREDGSLTIRARRHPHTEHVQQTFRTEIKI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_055239
RefSeq Size	2908
RefSeq ORF	510
Synonyms	cvHSP
Locus ID	27129
Cytogenetics	1p36.13
Summary	This gene encodes a small heat shock family B member that can heterodimerize with similar heat shock proteins. Defects in this gene are associated with advanced heart failure. In addition, the encoded protein may be a tumor suppressor in the p53 pathway, with defects in this gene being associated with renal cell carcinoma. [provided by RefSeq, Mar 2017]

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