NC2 alpha (DRAP1) (NM_006442) Human Mass Spec Standard

CAT#: PH304031

DRAP1 MS Standard C13 and N15-labeled recombinant protein (NP_006433)



  View other "NC2 alpha" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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    • 100 ug

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Specifications

Product Data
Description DRAP1 MS Standard C13 and N15-labeled recombinant protein (NP_006433)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204031
Predicted MW 22.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_006433
RefSeq Size 1022
RefSeq ORF 615
Synonyms NC2-alpha
Locus ID 10589
Cytogenetics 11q13.1
Summary Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008]
Protein Families Transcription Factors
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