AADACL1 (NCEH1) (NM_020792) Human Mass Spec Standard

Specifications

Product Data
Description	NCEH1 MS Standard C13 and N15-labeled recombinant protein (NP_065843)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206188
Predicted MW	49.1 kDa
Protein Sequence	Sequence Link (showhide) >RC206188 protein sequence Red=Cloning site Green=Tags(s) MSSCRGQKVAGGLRVVSPFPLCQPAGEPSRGKMRSSCVLLTALVALAAYYVYIPLPGSVSDPWKLMLLDA TFRGAQQVSNLIHYLGLSHHLLALNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRS VVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKY MVDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVM VKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQ LLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPT NFSVGIRTRNSYIKWLDQNL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_065843
RefSeq Size	4294
RefSeq ORF	1320
Synonyms	AADACL1; NCEH
Locus ID	57552
Cytogenetics	3q26.31
Summary	Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.[UniProtKB/Swiss-Prot Function]
Protein Families	Transmembrane

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