ERAS (NM_181532) Human Mass Spec Standard

Specifications

Product Data
Description	ERAS MS Standard C13 and N15-labeled recombinant protein (NP_853510)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210965
Predicted MW	25.3 kDa
Protein Sequence	Sequence Link (showhide) >RC210965 protein sequence Red=Cloning site Green=Tags(s) MELPTKPGTFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVEDH DPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSLIQLQQIWATWGP HPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEP MARSCREKTRHQKATCHCGCSVA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_853510
RefSeq Size	826
RefSeq ORF	699
Synonyms	HRAS2; HRASP
Locus ID	3266
Cytogenetics	Xp11.23
Summary	This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]
Protein Families	Druggable Genome

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