Cdhr2 (NM_001033364) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR215330 representing NM_001033364 Red=Cloning site Green=Tags(s) MAWLWLLCALLPAFMVSVTANSPPSFGVNMTLVTLPEDLPVGAVAFWLVATDSDNDHLTYGISGPNASYF SVNANTGEVKLASPLDFETVPFFKITISTSDGLNIRTAEMQVIVEDRNDNIPVFLNTEFSTSINETLPVG SVVFSVLAEDKDTGTAGLVQYFIEKVIPSTANSNNLFRILENGSIVLNDTLSYNNKSAFYQLELKACDSG GILDNKPKTQCSQPVFVSISVIDEPDLDPRFIREFYSASVAEDATLGTSVLTVEAVDSDKGINDIVTYSV SNSTRPGWFDIREDGVIFVNGSLDREQLLLENEEVQIQVTATEKNLNIYGQEAKASMWVTIRVTDVNDHK PEFYNCSLPGCSFSPQEAQVNFIGYVDEHASARISIDGLTMVAYDPDQGDNGTFLLSLNGQDAEAFNVSP ERAAGSVSVQVVVRNSEMVDYEKETVMVVEVVATDSVSNNYSVATVTIHLRNINDHRPVFSQSLYELTVP EHCPTGYLVTDKIQATDLDGDEWGPITYSLLPGNGADLFEVEPNSGNLTVKNGTLLDREKQAVYYLTLQA TDGGNQSTTTALEITLLDINDNPPVVRGSYNVFVPEENGNVSVTIQAYDDDQPDTNNSLLVFSLLPGPYS SNFSLDPNTGLLRNLGPLDREAIDPALEGRIVLTVIVADCGEPSLSTNVNVTITVEDINDNLPVFNQSYE FSVWERVPGAWVGTVKAWDADQTAANNRISFSLSGTGANNFILQGNVLEQGWAEGSLWLLPDVRLDYETQ KFFHLTVSAENPGPQGLDSTANVTVTVMDVNDEPPTLDAASLQAISVTENGSEHGQVTRVIAQDVDTAAL LRIELVDVICTKAGVDVGSVCHGWFSVDGNGSVYINQSEAIDYEACHLVTLVVRAYDLNTDPGFDAYSSN GSLLINIKDKNDNAPYFLPNNQTFVIIPELVLPNQQVASVQARDEDSEDNGIIMFSILKAEFVRKDGTSN PVQVFRITRSVEAGLFTGSIELVTNLDSTIQGTYQVTVQAQDQPTLGPALETQTTLNLFTVDQSYRVRLQ FSTSKEDVGANMEEIKEALIQATRTSVYVVTIQNIDSTARARASSYMDAYFVFSNGTALTLTELNMMIRK DQDALRQLLQLGLVVVSSQESQEPDQQKLLTSVIIGLVVSLVLVLVILITALVCLRKSYHRKLRAMKAGK EARKTPIETTAPTAAIPGTNMYNTDRANPVLDLPTKDLGLECHSSSDLDYDSLNSLDENSVDLDMDSKEF KRKDLPGDPPEPDPEPLTAVLSGRSAGASEQQKKNLSFTNPGLDTTDL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	143.1 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001028536
Locus ID	268663
UniProt ID	E9Q7P9
Refseq Size	4131
Cytogenetics	13 B1
Refseq ORF	3924
Synonyms	Gm624; PC-LKC; Pcdh24
Summary	Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells.[UniProtKB/Swiss-Prot Function]

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