Pacs2 (NM_001081170) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR217361 representing NM_001081170 Red=Cloning site Green=Tags(s) MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLAVLRELEKELLSVVIAVKMQG SKRVLRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAAGSINMA EVMQHPSEGGQVLSLCSSIKEASVKVAEIWIVSLSSQPIDHEDSAMQAGPKTKSTDNYSEEEYESFSSEQ EASDDAVQGQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQNFKQKVVALLRRFKVSEEVLDSEQDPAEHVP EVEEDLDLLYDTLDVENPSDSGPDMDDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHREPPSP ADVPEKTRSLGGKQQLSDSVSDTVALSAAVPREPSGQPEDSPEAETSTLDVFTEKLPPSGRIIKTESLVI PSTRSESKPAGRRGRSTSLKERQPARPQNERANSLDNERCPDTRSQLQIPRKTVYDQLNHILISDDQLPE NIILVNTSDWQGQFLSDVLQKHTLPVVCTCSAADVQAAFSTIVSRIQRYCNCNSQPPTPVKIAVAGAQHY LSAILRLFVEQLSHKTPDWLGYMRFLIIPLGSHPVARYLGSVDYRYNNFFQDLAWRDLFNKLEAQSSVQD TPDIVSRITQYISGANCAHQLPIAEAMLTYKQKSPDEESSQRFIPFVGVVKVGIVEPSSATSGDSDDAAP SSSSILSSTPPSASTSPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKK DMPTTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKTKDKEVESKSQCIEGISR LICTAKHQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	98.6 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001074639
Locus ID	217893
UniProt ID	E9Q7E9
Refseq Size	5480
Cytogenetics	12 F1
Refseq ORF	2676
Synonyms	6720425G15Rik; AW208651; AW489976; E230011J22; mKIAA0602; Pacs1l
Summary	Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments (By similarity).[UniProtKB/Swiss-Prot Function]

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