Ctla4 (NM_009843) Mouse Recombinant Protein
CAT#: TP723873
Purified recombinant protein of Mouse cytotoxic T-lymphocyte-associated protein 4 (Ctla4)
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CNY 3,210.00
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Specifications
Product Data | |
Species | Mouse |
Expression Host | CHO |
Expression cDNA Clone or AA Sequence |
Mouse CTLA-4, the region of Ala37-Phe162, from gene Accession# NM_009843
|
Tag | Fc chimera |
Predicted MW | 41 kDa |
Concentration | lot specific |
Purity | >95%, as determined by Coomassie stained SDS-PAGE |
Buffer | 1 x PBS |
Storage | Store at -80°C. |
Stability | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
Bioactivity | Recombinant mouse CTLA-4 inhibits the production of IL-2 induced by 0.5 μg/mL of CD80 on Jurkat cells in a dose-dependent manner. The ED50 for this effect 50 is 5 - 30 ng/mL. |
Endotoxin | Less than 0.01 ng per µg protein as determined by the LAL method |
Reference Data | |
RefSeq | NP_033973 |
Locus ID | 12477 |
UniProt ID | P09793, Q6GTR6 |
Refseq Size | 1933 |
Cytogenetics | 1 30.58 cM |
Refseq ORF | 669 |
Synonyms | Cd152; Ctla; Ctla-4; Ly-5; Ly-56 |
Summary | This gene is a member of the immunoglobulin superfamily, and encodes a protein that functions as a negative regulator of T-cell responses. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013] |
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