NKG2C (KLRC2) Human Recombinant Protein

CAT#: TP724625

Recombinant Human NKG2C & CD94 Heterodimer



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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经常一起买 (1)
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Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Tag N-8His&N-FLAG
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Note Recombinant Human NKG2C/CD94 is produced by Human 293 Cells. The target gene encoding E98-L231&; S34-I179 is expressed with a 8His &; a FLAG tag at the N terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 3822
UniProt ID P26717
Synonyms NKG2C & CD94
Summary NKG2-C contains C-type lectin domain and belongs to the killer cell lectin-like receptor (KLR) family. KLR family is a group of transmembrane proteins preferentially expressed in natural killer (NK) cells. NK cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. CD94, also known as killer cell lectin-like receptor subfamily D member 1 (KLRD1), is expressed on the surface of NK cells in the innate immune system. CD94 plays a role as a receptor for the recognition of MHC class I Human Leukocyte Antigen (HLA)-E molecules by NK cells and some cytotoxic T-cells. CD94 can form disulfide-bonded heterodimer with NKG2C on the surface of NK cells. The CD94/NKG2C complex interacts with HLA-E on target cells and inhibit the cytotoxic activity of NK cells to prevent cell lysis.
Protein Families Transmembrane
Protein Pathways Antigen processing and presentation, Natural killer cell mediated cytotoxicity
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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