Elastase 3A (CELA3A) Human Recombinant Protein
CNY 3,140.00
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Specifications
Product Data | |
Species | Human |
Protein Source | Human 293 |
Expression cDNA Clone or AA Sequence |
Ser16-His270
|
Tag | C-6His |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 10%Glycerol, pH7.5 |
Note | Recombinant Human Chymotrypsin-Like Elastase Family Member 3A is produced by our Mammalian expression system and the target gene encoding Ser16-His270 is expressed with a 6His tag at the C-terminus. |
Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 10136 |
UniProt ID | P09093 |
Synonyms | Chymotrypsin-Like Elastase Family Member 3A; Elastase IIIA; Elastase-3A; Protease E; CELA3A; ELA3; ELA3A |
Summary | Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that belongs to the subfamily of serine proteases. Serine proteases hydrolyze many proteins in addition to elastin. ELA3A is secreted from the pancreas as a zymogen. Humans have six elastase genes that encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, ELA3A has little elastolytic activity. However, ELA3A is an efficient protease that preferentially cleaves proteins after alanine residues. Elastase 3A may also engage in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. |
Protein Families | Druggable Genome, Protease |
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