TRMT12 (NM_017956) Human Recombinant Protein
CAT#: TP760113
Recombinant protein of human tRNA methyltransferase 12 homolog (S. cerevisiae) (TRMT12), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
View other "TRMT12" proteins (2)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length TRMT12
|
Tag | N-His |
Predicted MW | 50.2 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_060426 |
Locus ID | 55039 |
UniProt ID | Q53H54 |
Refseq Size | 2232 |
Cytogenetics | 8q24.13 |
Refseq ORF | 1344 |
Synonyms | TRM12; TYW2 |
Summary | Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008] |
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